NCT03378544: ENGAGE-TBA

Engaging Traditional Birth Attendants to Reduce Maternal Depression in Rural Kenya

Completed NA Last updated 3 October 2025

What this trial tests

NA trial testing mhGAP in Depression in 220 participants. Completed in 31 August 2019.

Timeline

9 April 2018

Primary endpoint
31 August 2019

31 August 2019

Quick facts

Lead sponsor	Africa Institute of Mental and Brain Health (AFRIMEB)
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	220
Start date	9 April 2018
Primary completion	31 August 2019
Estimated completion	31 August 2019
Sites	1 location across Kenya

Drugs / interventions tested

• mhGAP

Conditions studied

• Depression — all drugs for Depression →

Sponsor

Africa Institute of Mental and Brain Health (AFRIMEB)

Who can join

Adults 14 to 50, female only, with Depression. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Evidence from Low and Middle Income Countries has demonstrated the effectiveness of various psychosocial approaches for depression. However, there are no mental health specialists to deliver these interventions especially in rural African settings. This study aims at testing the effectiveness of mental health Global Action Programme (mhGAP-IG) psychosocial interventions among Traditional Birth Attendants (TBAs) for pregnant mothers. The outcomes of this intervention will result into depression reduction in the mothers that will lead to better care during pregnancy and for their infants, allowing for long-term impact on their physical and the psychological wellbeing and that of their children.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Primary-level worker interventions for the care of people living with mental disorders and distress in low- and middle-income countries.
   van Ginneken N, Chin WY, Lim YC, Ussif A, et al · · 2021 · cited 89× · PMID 34352116 · DOI 10.1002/14651858.cd009149.pub3