Last reviewed · How we verify
NCT03377374
L. Reuteri ATCC PTA 5289 & L. Reuteri DSM 17938 for the Treatment of Children With Pharyngitis and/or Tonsillitis
NA trial testing Probiotic in Pharyngitis in 70 participants. Completed in 11 February 2019.
30 May 2018
Quick facts
| Lead sponsor | Innovacion y Desarrollo de Estrategias en Salud |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 70 |
| Start date | 28 December 2017 |
| Primary completion | 30 May 2018 |
| Estimated completion | 11 February 2019 |
| Sites | 1 location across Mexico |
Drugs / interventions tested
- Probiotic
- Placebo
Conditions studied
- Pharyngitis — all drugs for Pharyngitis →
- Tonsillitis — all drugs for Tonsillitis →
Sponsor
Innovacion y Desarrollo de Estrategias en Salud — full company profile →
Who can join
Adults 6 Months to 5, any sex, with Pharyngitis or Tonsillitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
RCT in children (6m to 5y) with pharyngitis and/or tonsillitis who will be allocated to receive for 10 days L. reuteri DSM 17938 + L. reuteri ATCC PTA 5289) at a dose of 2x10\^8 Colony Forming Units (CFU). Five drops are to be taken twice a day (in the morning and in the evening) or placebo drops, as treatment for clinical condition. Duration of symptoms and reduction of pain (odynophagia) severity during treatment will be measured as primary outcome
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03377374
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Probiotic
Trials testing the same drug.
- NCT07529457 — Akk09 in Adults With Constipation · NA · not yet recruiting
- NCT07507955 — Probiotics for Constipation Relief in Adults · NA · not yet recruiting
- NCT07462481 — Probiotic Improve Constipation · NA · recruiting
- NCT07511855 — Stress-buffering and Sleep Disturbance-resilient Effects of a Dual Bifidobacterium Longum Combination Under Short-term T · Phase 2 · not yet recruiting
- NCT07474064 — Probiotics Combined With Targeted Therapy Plus Immunotherapy in Bladder-Preserving Setting for Patients With MIBC · Phase 2 · not yet recruiting
Other recruiting trials for Pharyngitis
Currently open trials in the same condition.
- NCT06859281 — Safety, Tolerability, and Pharmacokinetic Profile of Grammidin, a Metered Dose Topical Spray in Healthy Volunteers · Phase 1 · recruiting
- NCT06857890 — Safety, Tolerability, and Pharmacokinetic Profile of Grammidin With Anesthetic, a Metered Dose Topical Spray in Healthy · Phase 1 · recruiting
- NCT06843018 — Study to Evaluate the Efficacy and Safety of Different Doses of Graminidin With Anesthetic, a Metered Dose Topical Spray · Phase 2 · recruiting
- NCT06114706 — Best Assessment of Sore Throat and Antibiotic Prescribing · NA · recruiting
- NCT04471493 — Pediatric and Ambulatory Research in Infectious Diseases · recruiting
Other Innovacion y Desarrollo de Estrategias en Salud trials
Trials by the same sponsor.
- NCT04265716 — Topical L. Reuteri in Children With Atopic Dermatitis · NA · unknown
- NCT03834415 — Lactobacillus Reuteri DSM17938 in C-Section Infants · NA · completed
- NCT04037826 — L. Reuteri DSM 17938 and L. Reuteri ATCC PTA 6475 in Moderate to Severe Irritable Bowel in Adults · NA · completed
- NCT03360253 — Clinical Trial of L. Reuteri in Infantile Colic 2017 · NA · unknown
- NCT03375125 — L. Reuteri ATCC PTA 5289 + L. Reuteri DSM 17938 in Pregnant Women · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03377374 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Innovacion y Desarrollo de Estrategias en Salud
- Last refreshed: 20 June 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03377374.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing