NCT03375723

Effects of Information and Breathing Technique - for Patients With Respiratory Pain in Acute Pulmonary Embolism.

Completed NA Last updated 29 February 2024

What this trial tests

NA trial testing Information on anatomy and physiology, and breathing technique in Pulmonary Embolism in 40 participants. Completed in 31 January 2024.

Timeline

1 October 2018

Primary endpoint
31 December 2023

31 January 2024

Quick facts

Lead sponsor	Göteborg University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	40
Start date	1 October 2018
Primary completion	31 December 2023
Estimated completion	31 January 2024
Sites	1 location across Sweden

Drugs / interventions tested

• Information on anatomy and physiology, and breathing technique
• Usual care treatment — full drug profile →

Conditions studied

• Pulmonary Embolism — all drugs for Pulmonary Embolism →

Sponsor

Göteborg University

Who can join

Adults 18 to 80, any sex, with Pulmonary Embolism. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Acute pulmonary embolism (PE) is a serious disease and the third most common cardiovascular disease following myocardial infarction and stroke. The most common symptoms of acute PE are breathlessness and respiratory pain. Although many patients have respiratory pain in acute PE, the treatment of pain is not well described in literature. It is also unclear how long after acute PE the respiratory pain persists. In other conditions with respiratory associated pain, clinical treatment guidelines are available to avoid complications, such as pneumonia, related to impaired respiratory function.

The purpose of this randomized controlled multicenter study is to evaluate the effect of a treatment, in patients with respiratory associated acute PE pain, consisting of information on anatomy and physiology in acute PE and breathing technique in addition to usual care treatment. The above treatment will be compared to conventional treatment in PE with respiratory associated pain, which means treatment with analgesics.

One hundred sixty patients recruited from the Sahlgrenska University Hospital and Alingsås Hospital will participate in the study.

Both groups are examined before and after interventions related to respiratory associated pain, measured with visual analogue scale (VAS), analgesic consumption, lung function measured with Peak Expiratory Flow (PEF), physical disability impairment measured by Disability Rating Index (DRI) and questions about the patients self-efficacy on managing their respiratory associated pain, days hospitalized, pneumonia rate during or after hospitalization, oxygen saturation and patient satisfaction.

Both groups are followed from the inclusion date to 14 days after inclusion through physical visits by the physiotherapist during hospital care and by telephone contact after discharge.

If the positive clinical experience of the information and breathing technique can be confirmed in the study, the method could be spread and used as an easily accessible new treatment method.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.