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NCT03374813
Efficacy of MimetikOss in Alveolar Ridge Preservation Previous to Implant Placement
NA trial testing MimetikOss (bone grafting surgery) in Alveolar Ridge Preservation in 102 participants. Status unknown.
22 April 2021
Quick facts
| Lead sponsor | Mimetis Biomaterials S.L. |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 102 |
| Start date | 16 November 2017 |
| Primary completion | 22 April 2021 |
| Estimated completion | 15 December 2021 |
| Sites | 8 locations across Chile, Spain |
Drugs / interventions tested
- MimetikOss (bone grafting surgery)
- Bio-Oss (bone grafting surgery)
Conditions studied
- Alveolar Ridge Preservation — all drugs for Alveolar Ridge Preservation →
Sponsor
Mimetis Biomaterials S.L.
Who can join
18 and older, any sex, with Alveolar Ridge Preservation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The hypothesis tested in this clinical trial is that a biomimetic synthetic bone graft substitute (MimetikOss, Mimetis Biomaterials) with similar properties to those of human bone can reach a clinical outcome non inferior to that of a deproteinized bovine bone matrix bone graft substitute (Bio-Oss, Geistlisch) in an alveolar ridge preservation procedure followed by implant placement in terms of bone volume changes (primary end point), bone histological observation implant stability and bone level changes (secondary end points).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Biomimetic and immunomodulatory therapeutics as an alternative to natural exosomes for vascular and cardiac applications.
Villarreal-Leal RA, Cooke JP, Corradetti B. · · 2021 · cited 13× · PMID 33774130 · DOI 10.1016/j.nano.2021.102385
Verify or expand the search:
- PubMed search for NCT03374813
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Alveolar Ridge Preservation
Currently open trials in the same condition.
- NCT07242313 — Comparison of Demineralized and Mineralized Dentin Grafts in Ridge Preservation · NA · recruiting
- NCT07526129 — Impact of Alveolar Ridge Preservation on the Potential Need for Sinus Floor Elevation: A 10-year Retrospective Radiograp · recruiting
- NCT06827665 — Clinical and Radiographic Evaluation of Allogenic Dentin Grafts for Alveolar Ridge Preservation · Phase 1, PHASE2 · recruiting
- NCT06784232 — Alveolar Ridge Preservation: Biologically-oriented Alveolar Ridge Preservation Vs Modified Periosteal Inhibition · active not recruiting
- NCT06141239 — 2D/3D Imaging to Analyze the Regeneration Rate of Autologous Bone · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03374813 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mimetis Biomaterials S.L.
- Last refreshed: 25 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03374813.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing