NCT03374436

Impact of Sprint Stair Climbing "Snacks" on Markers of Metabolism and Vascular Function

Completed NA Last updated 25 September 2019

What this trial tests

NA trial testing High-Carbohydrate Sedentary in Physical Activity in 23 participants. Completed in 30 August 2019.

Timeline

1 October 2017

Primary endpoint
30 June 2019

30 August 2019

Quick facts

Lead sponsor	University of British Columbia
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	other
Enrollment	23
Start date	1 October 2017
Primary completion	30 June 2019
Estimated completion	30 August 2019
Sites	1 location across Canada

Drugs / interventions tested

• High-Carbohydrate Sedentary
• High-Carbohydrate Active
• Low-carbohydrate Sedentary

Conditions studied

• Physical Activity — all drugs for Physical Activity →
• Diet Modification — all drugs for Diet Modification →

Sponsor

University of British Columbia

Who can join

Adults 18 to 65, any sex, with Physical Activity or Diet Modification. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Prolonged sitting has been shown to impair metabolism and vascular function. The overall purpose of this study is to determine if breaking up prolonged (9 hours) of sitting with brief (\~20 second) stair climbing exercise "snacks" can improve markers of metabolic control and vascular health in healthy young male participants and in males or females with overweight/obesity who are at risk of insulin resistance. An additional purpose is to determine if saliva insulin can be used as a valid indicator of blood insulin when measured throughout the day in sedentary and active conditions and when diets with different amounts of carbohydrates are consumed.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Hourly staircase sprinting exercise "snacks" improve femoral artery shear patterns but not flow-mediated dilation or cerebrovascular regulation: a pilot study.
   Caldwell HG, Coombs GB, Rafiei H, Ainslie PN, et al · · 2021 · cited 22× · PMID 33242251 · DOI 10.1139/apnm-2020-0562
2. Saliva insulin tracks plasma insulin across the day following high-carbohydrate and low-carbohydrate meals.
   Rafiei H, Omidian K, Chang CR, Little JP. · · 2023 · cited 6× · PMID 37262929 · DOI 10.1139/apnm-2023-0066