Who is sponsoring NCT03371680?

NCT03371680 is sponsored by University of Padova.

What drugs are being tested in NCT03371680?

Interventions in NCT03371680: Injection of 1-13 Carbon Leucine and deuterated water.

What condition does NCT03371680 study?

NCT03371680 studies ARDS, Sepsis Syndrome.

Is NCT03371680 still recruiting?

NCT03371680 is currently completed. Last updated 12 December 2017.

Last reviewed 2017-12-12 · How we verify

NCT03371680

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Kinetics of Disaturated-phosphatidylcholine and Specific Surfactant Proteins Turnover, Water Turnover and Total Body Water in Acute Respiratory Distress Syndrome (ARDS) in Intensive Care Unit (ICU) Patients and in Control Patients

Completed NA Last updated 12 December 2017

What this trial tests

NA trial testing Injection of 1-13 Carbon Leucine and deuterated water in ARDS in 21 participants. Completed in 31 December 2013.

Timeline

1 October 2010

Primary endpoint
31 December 2013

31 December 2013

Quick facts

Lead sponsor	University of Padova
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	basic science
Enrollment	21
Start date	1 October 2010
Primary completion	31 December 2013
Estimated completion	31 December 2013

Drugs / interventions tested

Injection of 1-13 Carbon Leucine and deuterated water — full drug profile →

Conditions studied

ARDS — all drugs for ARDS →
Sepsis Syndrome — all drugs for Sepsis Syndrome →

Sponsor

University of Padova

Who can join

Adults 18 to 76, any sex, with ARDS or Sepsis Syndrome. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Disaturated phosphatidylcholine (DSPC) fractional synthesis rate
Time frame: 48 hours
DSPC deuterium incorporation, change from baseline. The following kinetic parameter will be calculated: fractional synthesis rate (expressed as percentage/day)

Sponsor's own description

Analysis of kinetics of phosphatidylcholine and specific surfactant proteins, total body water and water turnover in patients with acute respiratory distress syndrome (ARDS) and in intensive care unit (ICU) patients by using non radioactive isotopes as deuterium and Carbon-13.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for ARDS

Currently open trials in the same condition.

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NCT07370610 — Electrical Impedance Tomography-Based Dynamic Ventilation-Perfusion Functional Phenotype Trajectory in Acute Respiratory · active not recruiting
NCT06647784 — Lateral Positioning and Prone Positioning in ARDS Patients · NA · recruiting

Other University of Padova trials

Trials by the same sponsor.

NCT07435064 — NURsing-led FRAILty Prevention and Care · NA · not yet recruiting
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NCT07259460 — Effects of Dexmedetomidine Target Controlled Infusion on Patient State Index Values and Electroencephalographic Spectrum · recruiting
NCT07385118 — Daily Fluctuations in Brain-Derived Neurotrophic Factor and Cognition: Effects of Vigorous Exercise · NA · completed
NCT07259291 — Minto and Eleveld Remifentanil Target Controlled Infusion (TCI) Models: a Clinical Comparison · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03371680 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Padova
Last refreshed: 12 December 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03371680.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing