NCT03370458 (DR7) is a NA clinical trial of Lactobacillus plantarum DR7 in Stress, sponsored by Universiti Sains Malaysia.

Who is sponsoring NCT03370458?

NCT03370458 is sponsored by Universiti Sains Malaysia.

What drugs are being tested in NCT03370458?

Interventions in NCT03370458: Lactobacillus plantarum DR7, Placebo.

Is NCT03370458 still recruiting?

NCT03370458 is currently completed. Last updated 3 July 2018.

Last reviewed 2018-07-03 · How we verify

NCT03370458: DR7

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Lactobacillus Plantarum DR7 for Gut-Brain-Axis Benefits

Completed NA Last updated 3 July 2018

What this trial tests

NA trial testing Lactobacillus plantarum DR7 in Stress in 118 participants. Completed in 31 March 2018.

Timeline

1 December 2017

Primary endpoint
31 March 2018

31 March 2018

Quick facts

Lead sponsor	Universiti Sains Malaysia
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	118
Start date	1 December 2017
Primary completion	31 March 2018
Estimated completion	31 March 2018
Sites	1 location across Malaysia

Drugs / interventions tested

Lactobacillus plantarum DR7
Placebo

Conditions studied

Stress — all drugs for Stress →

Sponsor

Universiti Sains Malaysia — full company profile →

Who can join

Adults 18 to 60, any sex, with Stress. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This project aims to study the benefits of probiotics namely Lactobacillus plantarum DR7 for brain health properties, primarily alleviation of stress, among adults in Malaysia aged from 18 to 60 years.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Microbiota and the gut-brain-axis: Implications for new therapeutic design in the CNS.
Liu L, Huh JR, Shah K. · · 2022 · cited 199× · PMID 35255456 · DOI 10.1016/j.ebiom.2022.103908
Gut Microbiome-Brain Alliance: A Landscape View into Mental and Gastrointestinal Health and Disorders.
Sasso JM, Ammar RM, Tenchov R, Lemmel S, et al · · 2023 · cited 100× · PMID 37156006 · DOI 10.1021/acschemneuro.3c00127
The Gut-Brain-Immune Axis in Glioma: Emerging Mechanisms and Therapeutic Opportunities.
Feng R, Yang Z, Zhou Y, Zhao H. · · 2026 · PMID 41677988 · DOI 10.1007/s10571-026-01680-3

Verify or expand the search:

Other recruiting trials for Stress

Currently open trials in the same condition.

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NCT07469527 — Effects of Feel Free® Classic Tonic on Stress and Pharmacokinetics in Healthy Adults · NA · recruiting
NCT07387107 — Decreasing Stress Via Virtual Reality and Binaural Beats in Non-Clinical Adults · NA · recruiting
NCT07240792 — Development of a College Student-Delivered Cognitive-Behavioral Therapy (CBT) Intervention for Rural High School Student · NA · recruiting
NCT07518056 — Relationships Between Nomophobia Levels and Perceived Stress, Body Image and Food Addiction Among University Students · recruiting

Other Universiti Sains Malaysia trials

Trials by the same sponsor.

NCT07397104 — Validity of a Self-reported Questionnaire for Periodontal Status in a Saudi Population · not yet recruiting
NCT07279324 — Safety and Efficacy of Kelulut Honey Eyedrops in Dry Eye Disease · NA · not yet recruiting
NCT07338045 — The Effects of Eight-Week Baduanjin Exercise on Chronic Low Back Pain and Disability Among Office Workers. · NA · not yet recruiting
NCT07410351 — Development of A Self-Assessment Tool for Personalized Preventive Periodontal Care Among the Saudi Population Using Semi · not yet recruiting
NCT07448909 — Cognitive-Frailty Gait Biomechanics for Early Dementia Detection · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03370458 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universiti Sains Malaysia
Last refreshed: 3 July 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03370458.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing