Last reviewed · How we verify
NCT03369925
Cognitive Effects of Citicoline in Men and Women With Age-Associated Memory Impairment
NA trial testing Placebo supplement in Healthy in 100 participants. Completed in 3 December 2018.
3 December 2018
Quick facts
| Lead sponsor | Kyowa Hakko Bio Co., Ltd. |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | basic science |
| Enrollment | 100 |
| Start date | 2 January 2018 |
| Primary completion | 3 December 2018 |
| Estimated completion | 3 December 2018 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Placebo supplement
- Citicoline supplement
Conditions studied
- Healthy — all drugs for Healthy →
Sponsor
Kyowa Hakko Bio Co., Ltd.
Who can join
Adults 50 to 85, any sex, with Healthy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objective of this trial is to determine the effects of citicoline on cognitive performance in healthy Men and Women with Age-Associated Memory Impairment compared to a placebo.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Choline supplements: An update.
Kansakar U, Trimarco V, Mone P, Varzideh F, et al · · 2023 · cited 55× · PMID 36950691 · DOI 10.3389/fendo.2023.1148166 -
Citicoline and Memory Function in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Nakazaki E, Mah E, Sanoshy K, Citrolo D, et al · · 2021 · cited 20× · PMID 33978188 · DOI 10.1093/jn/nxab119
Verify or expand the search:
- PubMed search for NCT03369925
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Citicoline supplement
Trials testing the same drug.
- NCT05200208 — Improving Sleep and Cognition in Alzheimer's Disease · NA · completed
- NCT04967157 — Cognitive Effects of Citicoline on Attention in Healthy Mean and Women · NA · completed
Other recruiting trials for Healthy
Currently open trials in the same condition.
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- NCT07496697 — Effects of Electroacupuncture at NP82 and SP15 on Bowel Motility in Healthy Subjects · NA · recruiting
- NCT06431932 — Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With Multimorbidity · Phase 1, PHASE2 · recruiting
Other Kyowa Hakko Bio Co., Ltd. trials
Trials by the same sponsor.
- NCT03444662 — The Combination Effect of Citicoline and Omega-3 · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03369925 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kyowa Hakko Bio Co., Ltd.
- Last refreshed: 27 February 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03369925.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing