Last reviewed · How we verify
NCT03365960: WM
Bioavailability and Pharmacokinetic Parameters of Watermelon (Rind, Flesh and Seeds) Polyphenols
NA trial testing Watermelon Rind in Healthy Subjects in 6 participants. Completed in 2 April 2019.
1 April 2019
Quick facts
| Lead sponsor | Clinical Nutrition Research Center, Illinois Institute of Technology |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | other |
| Enrollment | 6 |
| Start date | 15 January 2018 |
| Primary completion | 1 April 2019 |
| Estimated completion | 2 April 2019 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Watermelon Rind
- Watermelon Flesh
- Watermelon Seeds
- Placebo
Conditions studied
- Healthy Subjects — all drugs for Healthy Subjects →
Sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology — full company profile →
Who can join
Adults 20 to 45, any sex, with Healthy Subjects. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The primary objectives of the study are outlined below: 1. To investigate the relative bioavailability and absorption/kinetic profile of polyphenols after consumption of watermelon rind, flesh and seeds, respectively in an acute pilot study. 2. To study the effects of watermelon intake on endothelial function using the FMD technique and to understand the relationship between plasma metabolites, including L-citrulline and arginine, and FMD responses.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03365960
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Healthy Subjects
Currently open trials in the same condition.
- NCT07222020 — Phase 1 Study of Intravaginal KB15A · Phase 1 · recruiting
- NCT07350538 — The Critical Link Between Gut Microbiome Dysfunction, Cravings and Relapse: RECLAIM-GUT TRIAL · NA · active not recruiting
- NCT07304791 — This is a Phase 1, Randomized, Single-blind, Placebo-controlled Study to Assess the Safety, Pharmacokinetics (PK), and P · Phase 1 · recruiting
- NCT07059858 — Bladder and Bowel Functions, Participation and Quality of Life in Children With Intellectual Disabilities · recruiting
- NCT07331389 — A Drug-Drug Interaction Study of HDM1002 and Metformin, Empagliflozin, Midazolam, Valsartan, and Warfarin · Phase 1 · recruiting
Other Clinical Nutrition Research Center, Illinois Institute of Technology trials
Trials by the same sponsor.
- NCT06986161 — Optimizing Mango's Glycemic Impact: Investigating Mango Consumption Timing in Prediabetic Individuals · NA · recruiting
- NCT06555952 — MegaNatural BP® GSE on Blood Pressure and Cardiometabolic Risk Factors · NA · recruiting
- NCT05898217 — Vitamin and Mineral Absorption From Milk and PBMAs · NA · active not recruiting
- NCT05892328 — Watermelon Dose Response Blood Pressure Study · NA · active not recruiting
- NCT05601635 — ButyraGen™, Short Chain Fatty Acids and Gut Microbiome · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03365960 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Clinical Nutrition Research Center, Illinois Institute of Technology
- Last refreshed: 14 July 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03365960.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing