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NCT03365843
Montage-Enhanced Sternal Closure
Phase 2 trial testing Montage bone putty in Sternal Closure in 65 participants. Status unknown.
1 December 2022
Quick facts
| Lead sponsor | University of Calgary |
|---|---|
| Phase | Phase 2 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 65 |
| Start date | 1 October 2018 |
| Primary completion | 1 December 2022 |
| Estimated completion | 1 December 2022 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Montage bone putty
- Conventional Sternal Closure
Conditions studied
- Sternal Closure — all drugs for Sternal Closure →
Sponsor
University of Calgary
Who can join
Adults 19 to 79, any sex, with Sternal Closure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Post-operative recovery after cardiac surgery is influenced by early sternal bone stability. Traditional sternal closure of median sternotomy usually entails the use of 6-10 stainless steel wires. Augmenting sternal closure with techniques to enhance early bone stability should accelerate functional recovery from cardiac surgery thereby reducing post-operative pain, decreasing the need for narcotics, improving breathing and chest wall mechanics, stimulating early mobility and expediting hospital discharge. This study is a randomized, single-centre, double-blind clinical study comparing the effects of Montage bone putty plus conventional wire closure vs conventional wire closure only on the post-operative recovery of cardiac surgery patients with full medial sternotomy.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Novel hardening bone putty enhances sternal closure and accelerates postoperative recovery.
Vasanthan V, Fatehi Hassanabad A, Kang S, Dundas J, et al · · 2023 · cited 3× · PMID 36272766 · DOI 10.1016/j.jtcvs.2022.09.016
Verify or expand the search:
- PubMed search for NCT03365843
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03365843 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Calgary
- Last refreshed: 28 September 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03365843.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing