NCT03365778

Educational Intervention to Adopt SLT as First-Line Glaucoma Treatment

Completed NA Results posted Last updated 30 January 2020

What this trial tests

NA trial testing Patient Educational Intervention in Primary Open-angle Glaucoma in 86 participants. Completed in 31 December 2019.

Timeline

23 October 2017

Primary endpoint
1 December 2018

31 December 2019

Quick facts

Lead sponsor	Wills Eye
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	other
Enrollment	86
Start date	23 October 2017
Primary completion	1 December 2018
Estimated completion	31 December 2019
Sites	1 location across United States

Drugs / interventions tested

• Patient Educational Intervention
• Usual Care
• Ophthalmologist Educational Intervention

Conditions studied

• Primary Open-angle Glaucoma — all drugs for Primary Open-angle Glaucoma →

Sponsor

Wills Eye — full company profile →

Who can join

Adults 40 to 90, any sex, with Primary Open-angle Glaucoma. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Completion of Selective Laser Trabeculoplasty (SLT) Primary · 1 hour

Percentage of patients who elect the Selective Laser Trabeculoplasty (SLT), as treatment for lowering eye pressure, compared between a group receiving SLT Educational Intervention and a Usual Care group. Follow-up eye examinations will be screened for a 6-month period to assess number of completed SLTs.

Group	Value	95% CI
Educational Intervention Group	10
Usual Care Group	6

Measure Educational Effects of Selective Laser Trabeculoplasty (SLT) Primary · 1 hour

Attitudes were assessed in the Patient Educational Intervention group before and immediately following intervention to determine how receptive they were regarding Selective Laser Trabeculoplasty (SLT) as a therapy to lowering eye pressure as compared to the more common therapy of daily eye drops.

Pre-Intervention Yes

Group	Value	95% CI
Educational Intervention Group	0
Usual Care Group	0

Post-Intervention Yes

Group	Value	95% CI
Educational Intervention Group	12
Usual Care Group	0

Measure Educational Effects of Selective Laser Trabeculoplasty (SLT) Among Ophthalmologists Secondary · 30 minutes

To evaluate barriers for widespread adoption of selective laser trabeculoplasty (SLT) as first line treatment of high eye pressure, we assessed the beliefs and attitudes of ophthalmologists regarding SLT. An educational slide presentation and survey targeted physicians to increase awareness and consideration of SLT earlier in the glaucoma treatment paradigm. Number of respondents who currently offer laser treatment for newly diagnosed glaucoma patients.

Group	Value	95% CI
Ophthalmologist Educational Intervention Group	45

Sponsor's own description

The purpose of this study is to develop an educational program that will help improve the patients' understanding of what laser treatment is, how it might be beneficial to them, and why it should be the first eye pressure lowering glaucoma treatment to consider before the use of glaucoma eye drops.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Educational intervention to adopt selective laser trabeculoplasty as first-line glaucoma treatment: Randomized controlled trial: Educational intervention on selective laser trabeculoplasty.
   Tran E, Sanvicente C, Hark LA, Myers JS, et al · · 2022 · cited 3× · PMID 34041935 · DOI 10.1177/11206721211018365