Last reviewed · How we verify
NCT03364413
Brain's Response to Chocolate
trial testing Chocolate in Overweight in 20 participants. Completed in 2 March 2018.
2 March 2018
Quick facts
| Lead sponsor | USDA Grand Forks Human Nutrition Research Center |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 20 |
| Start date | 17 January 2018 |
| Primary completion | 2 March 2018 |
| Estimated completion | 2 March 2018 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Chocolate
Conditions studied
- Overweight — all drugs for Overweight →
- Obesity — all drugs for Obesity →
Sponsor
USDA Grand Forks Human Nutrition Research Center
Who can join
Adults 18 to 50, any sex, with Overweight or Obesity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to test how the brain responds when individuals eat enjoyable foods such as chocolate. Eating certain foods can make one want to keep eating even when feeling full, caused by dopamine in the brain. The researchers believe this dopamine response can be measured by looking at the individual's eye.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Increasing Chocolate's Sugar Content Enhances Its Psychoactive Effects and Intake.
Casperson SL, Lanza L, Albajri E, Nasser JA. · · 2019 · cited 11× · PMID 30870996 · DOI 10.3390/nu11030596
Verify or expand the search:
- PubMed search for NCT03364413
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Chocolate
Trials testing the same drug.
- NCT04037020 — The Chocolate Study 2.0 · completed
- NCT04367493 — Effects of Chocolate Consumption in Elderly Patients With Cancer in Palliative Care · NA · completed
Other recruiting trials for Overweight
Currently open trials in the same condition.
- NCT07509307 — AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee · Phase 3 · recruiting
- NCT07472881 — Multi-Acupoint Laser Therapy for Body Shape and Composition in Obese Menopausal Women · NA · recruiting
- NCT07465965 — A Clinical Study of Semaglutide Nasal Spray in Overweight or Obese Adults · Phase 1 · recruiting
- NCT07407348 — A Study in People With Overweight or Obesity to Compare How 2 Different Formulations of Survodutide Are Taken up by the · Phase 1 · recruiting
- NCT07400653 — A Study to Learn About the Study Medicine (PF-08653944) in People With Obesity or Overweight and Type 2 Diabetes (T2D) · Phase 3 · recruiting
Other USDA Grand Forks Human Nutrition Research Center trials
Trials by the same sponsor.
- NCT06674642 — Traditional Indigenous Foods Diet and Health Study · NA · completed
- NCT06123208 — Impact of Eating Beans on Metabolism · NA · completed
- NCT05612412 — Exercise for Better Bones - Day or Night? · NA · terminated
- NCT05938894 — Train Your Brain - Executive Function · NA · completed
- NCT06096636 — National Survey of Young Adult Nutrition · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03364413 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by USDA Grand Forks Human Nutrition Research Center
- Last refreshed: 8 December 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03364413.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing