NCT03360500

Cryotherapy Associated With Exercise in Pain Control and Physical Function in Individuals With Knee Osteoarthritis

Completed NA Last updated 27 September 2024

What this trial tests

NA trial testing EXERCISE PROTOCOL + CRYOTHERAPY in Osteoarthritis,Knee in 120 participants. Completed in 24 August 2023.

Timeline

26 March 2018

Primary endpoint
24 August 2023

24 August 2023

Quick facts

Lead sponsor	Universidade Federal de Sao Carlos
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	prevention
Enrollment	120
Start date	26 March 2018
Primary completion	24 August 2023
Estimated completion	24 August 2023
Sites	1 location across Brazil

Drugs / interventions tested

• EXERCISE PROTOCOL + CRYOTHERAPY
• EXERCISE PROTOCOL
• EXERCISE PROTOCOL + PLACEBO

Conditions studied

• Osteoarthritis,Knee — all drugs for Osteoarthritis,Knee →

Sponsor

Universidade Federal de Sao Carlos

Who can join

Adults 40 to 75, any sex, with Osteoarthritis,Knee. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to verify the effect of cryotherapy associated with an exercise protocol in pain control, function and quality of life in individuals with knee osteoarthritis

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

1. Adjunctive therapies in addition to land-based exercise therapy for osteoarthritis of the hip or knee.
   French HP, Abbott JH, Galvin R. · · 2022 · cited 12× · PMID 36250418 · DOI 10.1002/14651858.cd011915.pub2
2. Photobiomodulation therapy associated with supervised therapeutic exercises for people with knee osteoarthritis: a randomised controlled trial protocol.
   S Jorge AE, O Dantas L, M S Serrão PR, Alburquerque-Sendín F, et al · · 2020 · cited 10× · PMID 32482669 · DOI 10.1136/bmjopen-2019-035711
3. Cryotherapy associated with tailored land-based exercises for knee osteoarthritis: a protocol for a double-blind sham-controlled randomised trial.
   Ogura Dantas L, Serafim Jorge AE, Regina Mendes da Silva Serrão P, Aburquerque-Sendín F, et al · · 2020 · cited 6× · PMID 32482668 · DOI 10.1136/bmjopen-2019-035610
4. Does cryotherapy associated with physical exercise add benefits to pain, function and quality of life in knee osteoarthritis? A randomized controlled trial
   Perea J, Viana Ferrari A, Almeida Silva H, Serafim Jorge A, et al · · 2026