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Electrical Activation Mapping Guided Tailor Made Approach for Cardiac Resynchronization Therapy
Background Cardiac Resynchronization Therapy (CRT) is proven to improve survival and heart function of patient with certain electrical conduction abnormality and heart failure. However, in patient with certain electrical conduction abnormality, a good response is observed in less than 40% in patient receiving CRT. Conventionally the surgical approach of CRT is to implant one pacing lead in the right heart and one in the left heart to resynchronize the contraction and the pacing lead in the left heart is usually placed in the posterior or lateral portion of the left heart. However, this single approach may not be optimal, especially for those patients with conduction abnormality known to have poor response to CRT. Purpose of the clinical investigation The purpose of the Electrical Activation Guided CRT Study is to study the effectiveness of a tailored made approach to CRT procedure by using a noninvasive globally mapping system studying the electrical conduction under different approaches to delivery CRT. The pacing approach that optimally corrects conduction abnormality will be determined before the actual implantation procedure. Conduct of the Investigation This study will include 93 patients with conduction abnormality that known to have a poor response to CRT from Prince of Wales Hospital, Hong Kong.Subjects will be followed up at 3 months and 6 months visit.
Details
| Lead sponsor | Chinese University of Hong Kong |
|---|---|
| Phase | NA |
| Status | UNKNOWN |
| Enrolment | 93 |
| Start date | Thu Mar 08 2018 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Sat Aug 31 2024 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Heart Failure
Interventions
- Noninvasive electrical dyssynchrony study
Countries
Hong Kong