Comparison of Therapeutic Effects Between Intravitreal Injection of Bevacizumab With Intravitreal Injection of Bevacizumab and Targeted Laser Photocoagulation of Non Perfused Areas of Retina in Patients With Acute Retinal Vein Occlusion (bevacizumab)

NCT03353324 Phase 2/Phase 3 UNKNOWN

Patients with new onset retinal vein occlusion in less than 3 month whom has visual acuity less than 20/40 and central macular thickness more than 250micrometer and non perfused areas of retina more than 10 DD are included in over study and devided into 2 groups randomizely, Group A under gone 3 intravitreal injection of bevacizumab monthly and examine monthly for Visual acuity and central macular thickness, if in month four or more the CMT is more than 250 micrometer and the visual acuity is less than 8/10 the injection is repeated and follow up in this manner is continued until 9 months. Group B is as the same of group A but patients in this group undergone laser photocoagulation of retinal non perfused areas based on FAG wide field imaging . After 9 month follow up the outcomes such as Vusal acuity, Central macular thickness, intraocular pressure, neovascular formation are compared,

Details

Lead sponsor	Shahid Beheshti University of Medical Sciences
Phase	Phase 2/Phase 3
Status	UNKNOWN
Enrolment	74
Start date	2017-11-01
Completion	2018-09

Conditions

• Retinal Vein Occlusion With Macular Edema

Interventions

• intravitreal injection of bevacizumab
• intravitreal injection of bevacizumab+ targeted laser

Primary outcomes

• Visual acuity — Every month
  Snellen chart

Countries

Iran