Study of Dasatinib in Combination With Everolimus for Children and Young Adults With Gliomas Harboring Platelet-Derived Growth Factor Receptor (PDGFR) Alterations

NCT03352427 PHASE2 TERMINATED Results posted

This trial will evaluate the activity of dasatinib in combination with everolimus for children with gliomas harboring PDGFR alterations, including newly diagnosed high-grade glioma (HGG) or diffuse intrinsic pontine glioma (DIPG) after radiation (stratum A); and recurrent/progressive glioma (grade II-IV, including DIPG) (stratum B).

Details

Lead sponsor	University of Michigan Rogel Cancer Center
Phase	PHASE2
Status	TERMINATED
Enrolment	3
Start date	Wed Dec 06 2017 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Wed May 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Glioma
• High Grade Glioma
• Pontine Tumors

Interventions

• Dasatinib
• Everolimus

Countries

United States