NCT03350945

Application of Carbon Nanoparticles in Laparoscopic Colorectal Surgery

Status unknown NA Last updated 22 November 2017

What this trial tests

NA trial testing Device: tumor localization in Colorectal Tumor in 150 participants. Status unknown.

Timeline

1 December 2017

Primary endpoint
1 August 2019

31 December 2019

Quick facts

Lead sponsor	Aiguo, Lu
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	150
Start date	1 December 2017
Primary completion	1 August 2019
Estimated completion	31 December 2019

Drugs / interventions tested

• Device: tumor localization

Conditions studied

• Colorectal Tumor — all drugs for Colorectal Tumor →

Sponsor

Aiguo, Lu

Who can join

Adults 18 to 80, any sex, with Colorectal Tumor. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The project aims to evaluate the safety, effectiveness, accuracy and economy efficiency of the application of carbon nanoparticles for tumor localization and lymph nodes mapping in the laparoscopic coloectal surgery.

Publications & conference data

8 peer-reviewed publications reference this trial (live from Europe PMC):

1. Nanotechnology in cancer diagnosis: progress, challenges and opportunities.
   Zhang Y, Li M, Gao X, Chen Y, et al · · 2019 · cited 227× · PMID 31847897 · DOI 10.1186/s13045-019-0833-3
2. Recent Trends of the Bio-Inspired Nanoparticles in Cancer Theranostics.
   Madamsetty VS, Mukherjee A, Mukherjee S. · · 2019 · cited 82× · PMID 31708785 · DOI 10.3389/fphar.2019.01264
3. A detailed insight of the tumor targeting using nanocarrier drug delivery system.
   Batool S, Sohail S, Ud Din F, Alamri AH, et al · · 2023 · cited 56× · PMID 36866455 · DOI 10.1080/10717544.2023.2183815
4. Image-guided cancer surgery: a narrative review on imaging modalities and emerging nanotechnology strategies.
   Bortot B, Mangogna A, Di Lorenzo G, Stabile G, et al · · 2023 · cited 34× · PMID 37202750 · DOI 10.1186/s12951-023-01926-y
5. Nanoparticles applied to cancer immunoregulation.
   Lopez-Campos F, Candini D, Carrasco E, Berenguer Francés MA. · · 2019 · cited 20× · PMID 30425606 · DOI 10.1016/j.rpor.2018.10.001
6. A shift in focus towards precision oncology, driven by revolutionary nanodiagnostics; revealing mysterious pathways in colorectal carcinogenesis.
   Sharma S, Bhattacharya S, Joshi K, Singh S. · · 2023 · cited 9× · PMID 37650995 · DOI 10.1007/s00432-023-05331-8
7. Nanomedicine for colon-targeted drug delivery: strategies focusing on inflammatory bowel disease and colon cancer.
   Kumar A, Vaiphei KK, Singh N, Datta Chigurupati SP, et al · · 2024 · cited 6× · PMID 39105753 · DOI 10.1080/17435889.2024.2350356
8. The Role of Inorganic Nanomaterials in Overcoming Challenges in Colorectal Cancer Diagnosis and Therapy.
   Wang J, Wang H, Zou F, Gu J, et al · · 2025 · cited 3× · PMID 40284405 · DOI 10.3390/pharmaceutics17040409