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NCT03346668
Role of Neurogenic Inflammation and Topical 6% Gabapentin Therapy in Symptomatic Scarring Alopecia
EARLY_PHASE1 trial testing Topical gabapentin in Scarring Alopecia in 5 participants. Completed in 11 October 2021.
11 October 2021
Quick facts
| Lead sponsor | University of Minnesota |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 5 |
| Start date | 28 January 2016 |
| Primary completion | 11 October 2021 |
| Estimated completion | 11 October 2021 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Topical gabapentin — full drug profile →
Conditions studied
- Scarring Alopecia — all drugs for Scarring Alopecia →
- Frontal Fibrosing Alopecia — all drugs for Frontal Fibrosing Alopecia →
- Lichen Planopilaris — all drugs for Lichen Planopilaris →
- Central Centrifugal Cicatricial Alopecia — all drugs for Central Centrifugal Cicatricial Alopecia →
Sponsor
University of Minnesota
Who can join
18 and older, any sex, with Scarring Alopecia or Frontal Fibrosing Alopecia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study will serve as a pilot study to determine the efficacy and safety of topical gabapentin in the treatment of symptomatic scarring alopecia.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Oral gabapentin for scalp pruritus in patients with lichen planopilaris: A case series.
Chen LC, Ogbutor C, Yıldız-Altay Ü, Kelley KJ, et al · · 2024 · PMID 39233792 · DOI 10.1016/j.jdcr.2024.06.022 -
Topical gabapentin and its relation to cutaneous innervation in symptomatic lymphocytic primary cicatricial alopecia
Bohjanen S, McAdams B, Mead N, Loavenbruck A, et al · · 2024
Verify or expand the search:
- PubMed search for NCT03346668
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03346668 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Minnesota
- Last refreshed: 25 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03346668.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing