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NCT03344757

Health Gatherings - For Your Health After Cancer

Completed NA Results posted Last updated 11 September 2025
What this trial tests

NA trial testing Cultural CBSM in Prostate Neoplasm in 188 participants. Completed in 1 August 2024.

Timeline
5 October 2017
Primary endpoint
1 August 2024
1 August 2024

Quick facts

Lead sponsorUniversity of Miami
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingdouble
Primary purposesupportive care
Enrollment188
Start date5 October 2017
Primary completion1 August 2024
Estimated completion1 August 2024
Sites2 locations across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of Miami

Who can join

18 and older, male only, with Prostate Neoplasm or Genital Neoplasms, Male. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Change in Symptom Burden as Measure by EPIC-S. Primary · Baseline, Month 3, Month 6, Month 12

Symptom Burden will be measured using the 5-item sexual domain of the Expanded Prostate Cancer Index Composite (EPIC) - Short Form (EPIC-S). All items are transformed to a 0-100 scale and averaged to calculate the domain summary scores, where higher scores indicate better functioning and less bother.

Baseline
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)30.1± 2.53
Cognitive Behavioral Stress Management (CBSM)32.1± 3.02
Month 3
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)34.7± 3.01
Cognitive Behavioral Stress Management (CBSM)35.8± 3.30
Month 6
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)35.9± 3.39
Cognitive Behavioral Stress Management (CBSM)38.0± 3.67
Month 12
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)36.2± 3.27
Cognitive Behavioral Stress Management (CBSM)38.9± 3.50
Change in HRQoL as Measured by the FACT Questionnaire. Primary · Baseline, Month 3, Month 6, Month 12

HRQoL will be measured using Functional Assessment of Cancer Therapy - Prostate (FACT-P) including 4 domains of the FACT-General (FACT-G). The questionnaire has 39 items, with the total score ranging from 0-156. Higher scores indicate better function.

Baseline
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)81.1± 1.12
Cognitive Behavioral Stress Management (CBSM)81.7± 1.70
Month 3
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)83.8± 1.30
Cognitive Behavioral Stress Management (CBSM)83.7± 1.45
Month 6
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)83.6± 1.51
Cognitive Behavioral Stress Management (CBSM)83.3± 1.74
Month 12
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)82.6± 1.41
Cognitive Behavioral Stress Management (CBSM)83.0± 1.54
Change in Symptom Burden as Measure by EPIC-UIN. Primary · Baseline, Month 3, Month 6, Month 12

Symptom Burden will be measured using the 9-item urinary domain of the Expanded Prostate Cancer Index Composite (EPIC) - Short Form (EPIC-UIN). All items are transformed to a 0-100 scale and averaged to calculate the domain summary scores, where higher scores indicate better functioning and less bother.

Baseline
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)73.5± 2.45
Cognitive Behavioral Stress Management (CBSM)78.8± 2.32
Month 3
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)77.4± 2.50
Cognitive Behavioral Stress Management (CBSM)82.2± 2.38
Month 6
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)79.5± 2.47
Cognitive Behavioral Stress Management (CBSM)84.6± 2.18
Month 12
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)78.3± 2.41
Cognitive Behavioral Stress Management (CBSM)83.3± 2.31
Change in HRQoL as Measured by the PROMIS Fatigue Questionnaire Primary · Baseline, Month 3, Month 6, Month 12

HRQoL will be measured using Patient-Reported Outcome Measurement Information System (PROMIS) short form for Fatigue Questionnaire. The PROMIS Fatigue measure generates t-scores with a mean of 50 and a standard deviation of 10. Scores typically range from approximately 30 to 80. Higher scores indicate greater fatigue.

Baseline
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)43.2± 0.90
Cognitive Behavioral Stress Management (CBSM)43.5± 0.99
Month 3
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)43.3± 0.88
Cognitive Behavioral Stress Management (CBSM)42.8± 1.06
Month 6
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)43.9± 1.09
Cognitive Behavioral Stress Management (CBSM)43.1± 1.05
Month 12
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)43.5± 0.96
Cognitive Behavioral Stress Management (CBSM)43.0± 0.99
Change in HRQoL as Measured by the PROMIS Pain Questionnaire Primary · Baseline, Month 3, Month 6, Month 12

HRQoL will be measured using the PROMIS short form for Pain Interference Questionnaire. The items are item banks, and scoring is done via a computer adaptive test (CAT), which utilizes item response theory (IRT) to calculate a score that is then transformed into a T-score with a mean of 50 and a standard deviation of 10. Scores typically range from approximately 30 to 80. Items are administered in an iterative approach where subsequent items are calibrated on prior ones. Once standard error reaches 2 or less, the CAT stops administering items. Higher scores indicate greater pain interference.

Baseline
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)47.8± 0.93
Cognitive Behavioral Stress Management (CBSM)47.0± 0.97
Month 3
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)46.7± 0.96
Cognitive Behavioral Stress Management (CBSM)46.4± 1.08
Month 6
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)47.1± 1.20
Cognitive Behavioral Stress Management (CBSM)46.9± 1.06
Month 12
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)48.3± 1.07
Cognitive Behavioral Stress Management (CBSM)46.2± 1.02
Change in Stress Management Skills as Measured by MOCS-A Secondary · Baseline, Month 3, Month 6, Month 12

Stress management skills will be measured using the Measure of Current Status Part A (MOCS-A) Questionnaire. MOCS-A is a 13-item questionnaire with a total score ranging from 0 - 52 with the higher score indicating greater stress management skills.

Baseline
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)38.5± 0.87
Cognitive Behavioral Stress Management (CBSM)37.6± 1.09
Month 3
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)38.6± 0.91
Cognitive Behavioral Stress Management (CBSM)38.3± 1.09
Month 6
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)39.6± 0.93
Cognitive Behavioral Stress Management (CBSM)39.3± 1.23
Month 12
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)39.2± 0.90
Cognitive Behavioral Stress Management (CBSM)38.0± 0.95
Change in Prostate Cancer-specific Psychological Distress as Measured by MAX-PC - Section I-II Secondary · Baseline, Month 3, Month 6, Month 12

Psychological distress will be measured using the Memorial Anxiety Scale for Prostate Cancer Patients (MAX-PC) Questionnaire. The MAX-PC sections I-II is a 14-item questionnaire with a total score ranging from 0-42 with the higher score indicating increased distress.

Baseline
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)7.1± 0.94
Cognitive Behavioral Stress Management (CBSM)10.0± 1.20
Month 3
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)5.6± 0.98
Cognitive Behavioral Stress Management (CBSM)6.2± 0.97
Month 6
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)5.01± 0.93
Cognitive Behavioral Stress Management (CBSM)7.7± 1.24
Month 12
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)6.7± 1.08
Cognitive Behavioral Stress Management (CBSM)6.1± 0.94
Change in Prostate Cancer-specific Psychological Distress as Measured by MAX-PC - Section III Secondary · Baseline, Month 3, Month 6, Month 12

Psychological distress will be measured using the Memorial Anxiety Scale for Prostate Cancer Patients (MAX-PC) Questionnaire. The MAX-PC section III is a 4-item questionnaire with a total score ranging from 0-12 with the lower score indicating increased distress.

Baseline
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)8.5± 0.28
Cognitive Behavioral Stress Management (CBSM)8.1± 0.37
Month 3
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)8.9± 0.31
Cognitive Behavioral Stress Management (CBSM)9.1± 0.33
Month 6
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)8.7± 0.29
Cognitive Behavioral Stress Management (CBSM)8.3± 0.38
Month 12
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)9.1± 0.30
Cognitive Behavioral Stress Management (CBSM)8.8± 0.35
Change in Psychosocial Distress as Measured by the PROMIS Depression Questionnaire Secondary · Baseline, Month 3, Month 6, Month 12

PROMIS-Depression is a 28-item questionnaire with a total score ranging from 28-140 with the higher score indicating increased symptoms of depression.

Baseline
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)44.8± 0.91
Cognitive Behavioral Stress Management (CBSM)45.9± 0.96
Month 3
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)43.8± 0.94
Cognitive Behavioral Stress Management (CBSM)44.7± 1.05
Month 6
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)44.8± 1.05
Cognitive Behavioral Stress Management (CBSM)45.4± 1.12
Month 12
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)45.5± 0.97
Cognitive Behavioral Stress Management (CBSM)44.9± 1.10
Change in Psychosocial Distress as Measured by the PROMIS Anxiety Questionnaire Secondary · Baseline, Month 3, Month 6, Month 12

PROMIS-Anxiety is a 29-item questionnaire with a total score ranging from 29-145 with the higher score indicating increased symptoms of anxiety.

Baseline
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)49.5± 0.98
Cognitive Behavioral Stress Management (CBSM)50.0± 1.08
Month 3
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)50.4± 0.96
Cognitive Behavioral Stress Management (CBSM)49.1± 1.18
Month 6
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)51.0± 1.16
Cognitive Behavioral Stress Management (CBSM)49.8± 1.24
Month 12
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)50.7± 0.98
Cognitive Behavioral Stress Management (CBSM)49.0± 1.15
Change in Interpersonal Function as Measured the SIP Questionnaire Secondary · Baseline, Month 3, Month 6, Month 12

Sickness Impact Profile (SIP) is a 20-item questionnaire responded with a yes or no. The total number of yes responses will be scored as 1 point with the total score ranging from 0-20 with the higher score indicating poor interpersonal function.

Baseline
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)2.5± 0.28
Cognitive Behavioral Stress Management (CBSM)3.1± 0.38
Month 3
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)2.6± 0.40
Cognitive Behavioral Stress Management (CBSM)2.9± 0.45
Month 6
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)2.2± 0.30
Cognitive Behavioral Stress Management (CBSM)2.5± 0.40
Month 12
GroupValue95% CI
Cultural-Cognitive Behavioral Stress Management (CCBSM)2.6± 0.38
Cognitive Behavioral Stress Management (CBSM)2.3± 0.36

Adverse events — posted to ClinicalTrials.gov

Time frame: 1 year. Reporting threshold: 0%. Adverse-event reports describe events observed during the trial — not all are caused by the drug.

Cultural-Cognitive Behavioral Stress Management (CCBSM)
Serious: 0/100 (0%)
Deaths: 0/100
Cognitive Behavioral Stress Management (CBSM)
Serious: 3/88 (3%)
Deaths: 0/88

Serious adverse events (3 terms)

ReactionSystemCultural-Cognitive Behavio…Cognitive Behavioral Stres…
InjuryInjury, poisoning and procedural complications
InsomniaPsychiatric disorders
HypertensionCardiac disorders
Other adverse events (6 terms — click to expand)

ReactionSystemCultural-Cognitive Behavio…Cognitive Behavioral Stres…
AnxietyPsychiatric disorders
DepressionPsychiatric disorders
COVID-19Infections and infestations
Gastroesophageal reflux diseaseGastrointestinal disorders
FallInjury, poisoning and procedural complications
InjuryInjury, poisoning and procedural complications

Most-reported serious reactions: Injury, Insomnia, Hypertension.

Data from ClinicalTrials.gov NCT03344757 adverse events section.

Sponsor's own description

The purpose of this study is to look at the effects of a 10-week stress management in-person group program. The program will study emotions, stress, and stress management techniques (such as relaxation and coping techniques) on quality of life, distress, depression, and physical health in Spanish- speaking, Hispanic/Latino men diagnosed with Prostate Cancer (PC).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Familism, family cohesion, and health-related quality of life in Hispanic prostate cancer survivors.
    Pedreira PB, Fleszar-Pavlović SE, Walsh EA, Noriega Esquives B, et al · · 2024 · cited 3× · PMID 38429598 · DOI 10.1007/s10865-024-00479-1

Verify or expand the search:

Other recruiting trials for Prostate Neoplasm

Currently open trials in the same condition.

Other University of Miami trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03344757.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing