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NCT03344133
Effect of Exercise Programme on Gut Microbiota, CVD Risk Factors and Appetite Regulation in Overweight Women
NA trial testing Exercise in Overweight and Obesity in 60 participants. Status unknown.
30 November 2017
Quick facts
| Lead sponsor | University of Glasgow |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | other |
| Enrollment | 60 |
| Start date | 16 September 2015 |
| Primary completion | 30 November 2017 |
| Estimated completion | 30 November 2017 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Exercise
Conditions studied
- Overweight and Obesity — all drugs for Overweight and Obesity →
Sponsor
University of Glasgow
Who can join
Adults 18 to 45, female only, with Overweight and Obesity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Evidence suggests that gut microbiota contributes to the development of atherosclerosis and therefore CVDs. Exercise has been extensively reported to be protective against CVDs due to modification of body fatness, metabolic risk factors and cardio-respiratory fitness. It remains unclear whether impact of exercise on CVD risk can be at least in part explained by changes in the microbiota. It also remains to be investigated whether modification of appetite and appetite hormones due to participation in exercise are related to changes in the gut microbiota composition. Therefore, this study will be conducted in overweight, healthy, sedentary women and will investigate the effect of a 4-week moderate intensity exercise programme on gut microbiota composition and metabolic activity, plasma concentrations of fasting and postprandial lipids, glucose, insulin and inflammatory markers, fasting and postprandial gut appetite hormones, subjective appetite measures and cardio-respiratory fitness.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03344133
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Overweight and Obesity
Currently open trials in the same condition.
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- NCT07406191 — WB-EMS Effects on Cardiometabolic Risk Factors · NA · recruiting
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Other University of Glasgow trials
Trials by the same sponsor.
- NCT07500792 — Effect of Early Time-Restricted Eating on Appetite, Appetite-Regulatory Hormones and Energy Intake · NA · not yet recruiting
- NCT07388121 — The Effect of Vitamin C Supplementation on Gut Microbiota Composition and Function in Healthy Adults · NA · recruiting
- NCT07130513 — Investigating the Feasibility of Krill Oil Intervention to Improve Muscle Function in Adults With Long-term Conditions · NA · recruiting
- NCT06895837 — Effect of Exercise on Appetite in Response to Meals During Energy Restriction · NA · recruiting
- NCT06939244 — Investigating the Effects of Krill Oil on the Recovery From Muscle Damaging Exercise: a Randomised Controlled Trial · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03344133 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Glasgow
- Last refreshed: 17 November 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03344133.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing