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NCT03341858: SK2

STRONG Kids 2: A Cells-to-Society Approach to Nutrition in Early Childhood

Active, enrolled Last updated 27 May 2022
What this trial tests

trial testing no intervention-strictly observational in Child Obesity in 450 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline
10 May 2013
Primary endpoint
20 August 2027
20 August 2027

Quick facts

Lead sponsorUniversity of Illinois at Urbana-Champaign
StatusActive, enrolled
Study typeOBSERVATIONAL
Enrollment450
Start date10 May 2013
Primary completion20 August 2027
Estimated completion20 August 2027

Drugs / interventions tested

Conditions studied

Sponsor

University of Illinois at Urbana-Champaign

Who can join

Adults 0 to 15, any sex, with Child Obesity or Child, Only. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

STRONG Kids 2: A Cells to Society Approach to Nutrition Overview Using a cells-to-society approach to nutrition, this transdisciplinary project will provide unique insights into how individual biology interacts with the family environment to promote healthy eating habits in young children. It is one of the first studies to take a longitudinal look at the habits, including milk and dairy consumption, from birth. STRONG Kids 2 is built upon previous research from STRONG Kids 1 with preschool-aged children, documenting the relationship among genetic, child, and family factors in predicting BMI and dietary habits. The study sample includes 450 infants and their families located in small urban communities in central Illinois. Biological samples and height and weight measurements from infants and toddlers are collected at 6 weeks, 3, 12, 18 months and 2, 3, 4, 5, 6, 7 and 8 years. Mothers are surveyed about weaning, dietary habits, household routines, children's emotions, feeding styles, and milk and dairy consumption. Additional measures such as maternal height and weight are also being collected.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

  1. The STRONG Kids 2 Birth Cohort Study: A Cell-to-Society Approach to Dietary Habits and Weight Trajectories across the First 5 Years of Life.
    Fiese BH, Musaad S, Bost KK, McBride BA, et al · · 2019 · cited 23× · PMID 30882062 · DOI 10.1093/cdn/nzz007
  2. Adherence to Screen Time and Physical Activity Guidelines is Associated with Executive Function in US Toddlers Participating in the STRONG Kids 2 Birth Cohort Study.
    McMath AL, Iwinski S, Shen S, Bost KF, et al · · 2023 · cited 14× · PMID 36027980 · DOI 10.1016/j.jpeds.2022.08.026
  3. Fecal Microbiome and Metabolomic Profiles of Mixed-Fed Infants Are More Similar to Formula-Fed than Breastfed Infants.
    Wang M, Valizadegan N, Fields CJ, Donovan SM. · · 2025 · cited 2× · PMID 39858934 · DOI 10.3390/microorganisms13010166
  4. Diet Patterns Featuring Western-Style and Low-Preparation Foods Differentially Relate to Cognitive Function in Early Childhood From the STRONG Kids 2 Birth Cohort Study.
    McMath AL, Keye SA, Barton JM, Cannavale CN, et al · · 2025 · PMID 40697196 · DOI 10.1016/j.cdnut.2025.107488

Verify or expand the search:

Other recruiting trials for Child Obesity

Currently open trials in the same condition.

Other University of Illinois at Urbana-Champaign trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03341858.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing