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NCT03341793: MYDIASECRET

Impact of Changes in Muscle Secretome in the Remission of Type 2 Diabetes Mellitus Induced by Bariatric Surgery

Status unknown NA Last updated 15 July 2019
What this trial tests

NA trial testing Muscle biopsy and blood test in Diabete Type 2 in 40 participants. Status unknown.

Timeline
14 November 2017
Primary endpoint
1 October 2021
1 October 2021

Quick facts

Lead sponsorCliniques universitaires Saint-Luc- Université Catholique de Louvain
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposebasic science
Enrollment40
Start date14 November 2017
Primary completion1 October 2021
Estimated completion1 October 2021
Sites1 location across Belgium

Drugs / interventions tested

Conditions studied

Sponsor

Cliniques universitaires Saint-Luc- Université Catholique de Louvain — full company profile →

Who can join

Adults 18 to 69, any sex, with Diabete Type 2. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Bariatric surgery is recognized as a therapeutic modality of type 2 diabetes. The mechanisms of this remission of diabetes remain poorly understood. The aim of our research is to characterize the changes in muscle secretome induced by bariatric surgery and to determine their role in improving the insulin sensitivity of skeletal muscle and insulin secretion by the B cell responsible for the remission of diabetes.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Secretome of Stromal Cancer-Associated Fibroblasts (CAFs): Relevance in Cancer.
    Mishra D, Banerjee D. · · 2023 · cited 24× · PMID 36831295 · DOI 10.3390/cells12040628
  2. 57<sup>th</sup> EASD Annual Meeting of the European Association for the Study of Diabetes.
    · 2021 · cited 11× · PMID 34468792 · DOI 10.1007/s00125-021-05519-y
  3. Identification of myokines susceptible to improve glucose homeostasis after bariatric surgery.
    Orioli L, Canouil M, Sawadogo K, Ning L, et al · · 2023 · cited 6× · PMID 37638789 · DOI 10.1093/ejendo/lvad122
  4. 58<sup>th</sup> EASD Annual Meeting of the European Association for the Study of Diabetes : Stockholm, Sweden, 19 - 23 September 2022.
    · 2022 · cited 6× · PMID 35920845 · DOI 10.1007/s00125-022-05755-w

Verify or expand the search:

Other recruiting trials for Diabete Type 2

Currently open trials in the same condition.

Other Cliniques universitaires Saint-Luc- Université Catholique de Louvain trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03341793.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing