NCT03335865 is a clinical trial in Acute Kidney Injury, sponsored by University of Utah.

Who is sponsoring NCT03335865?

NCT03335865 is sponsored by University of Utah.

What condition does NCT03335865 study?

NCT03335865 studies Acute Kidney Injury.

Is NCT03335865 still recruiting?

NCT03335865 is currently completed. Last updated 26 April 2023.

Last reviewed 2023-04-26 · How we verify

NCT03335865

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Noninvasive Measurements of Renal Perfusion During Cardiac Surgery

Completed Last updated 26 April 2023

What this trial tests

trial in Acute Kidney Injury in 100 participants. Completed in 12 September 2019.

Timeline

1 March 2018

Primary endpoint
12 September 2019

12 September 2019

Quick facts

Lead sponsor	University of Utah
Status	Completed
Study type	OBSERVATIONAL
Enrollment	100
Start date	1 March 2018
Primary completion	12 September 2019
Estimated completion	12 September 2019
Sites	1 location across United States

Conditions studied

Acute Kidney Injury — all drugs for Acute Kidney Injury →

Sponsor

University of Utah

Who can join

18 and older, any sex, with Acute Kidney Injury. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to assess the feasibility of measuring urine oxygen tension in cardiac surgery patient and the ability of peri-operative urine oxygen measurements to predict post-operative acute kidney injury. The hypothesis is that a small oxymeter placed in a urinary catheter will provide reliable measurement of urine oxygenation and that these measurements will predict post-operative acute kidney injury in cardiac surgery patients.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

Noninvasive Urine Oxygen Monitoring and the Risk of Acute Kidney Injury in Cardiac Surgery.
Silverton NA, Lofgren LR, Hall IE, Stoddard GJ, et al · · 2021 · cited 46× · PMID 34329393 · DOI 10.1097/aln.0000000000003663
Intraoperative Urinary Biomarkers and Acute Kidney Injury After Cardiac Surgery.
Silverton NA, Hall IE, Melendez NP, Harris B, et al · · 2021 · cited 12× · PMID 33549487 · DOI 10.1053/j.jvca.2020.12.026
Intraoperative Urine Oxygen in Cardiac Surgery and 12-Month Outcomes.
Parry SR, Silverton NA, Hall IE, Stoddard GJ, et al · · 2023 · cited 4× · PMID 36700909 · DOI 10.34067/kid.0003972022
The impact of urine flow on urine oxygen partial pressure monitoring during cardiac surgery.
Lofgren LR, Silverton NA, Kuck K, Hall IE. · · 2023 · cited 3× · PMID 35648329 · DOI 10.1007/s10877-022-00843-z
Therapeutic remodeling of the ceramide backbone prevents kidney injury.
Nicholson RJ, Cedeño-Rosario L, Maschek JA, Lonergan T, et al · · 2026 · cited 2× · PMID 41232539 · DOI 10.1016/j.cmet.2025.10.006

Verify or expand the search:

Other recruiting trials for Acute Kidney Injury

Currently open trials in the same condition.

NCT07273838 — Sodium-Glucose Cotransporter-2 Inhibitor for Patients With Acute Cardiorenal Syndrome · Phase 2 · recruiting
NCT07262320 — Epidemiology and Processes of Care for Renal Replacement Therapy in Acute Kidney Injury in Latin America · recruiting
NCT07351149 — Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery · recruiting
NCT07215702 — A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kid · Phase 2 · recruiting
NCT06654193 — Allogeneic HB-adMSCs vs Placebo for the Treatment of Acute Kidney Injury · Phase 1, PHASE2 · recruiting

Other University of Utah trials

Trials by the same sponsor.

NCT07515755 — Supplemental Oxygen and Oxygen Desaturations in Colonoscopies · NA · not yet recruiting
NCT07225426 — Personalizing Financial Incentives · NA · recruiting
NCT06716411 — Confirming the Effects of Acupuncture Treatments to Relieve Symptoms of Gulf War Illness · NA · recruiting
NCT07246538 — Positive Airway Pressure (PAP) System Evaluation in Volunteers · NA · not yet recruiting
NCT04208984 — Diversion Device With Breath Control · withdrawn

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03335865 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Utah
Last refreshed: 26 April 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03335865.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing