NCT03333070

The Use of Lactobacillus Reuteri in Functional Constipation in Children

Terminated NA Last updated 4 October 2018

What this trial tests

NA trial testing probiotic - Lactobacillus reuteri in Functional Constipation in 50 participants. Terminated before completion.

Timeline

26 June 2018

Primary endpoint
26 June 2018

26 June 2018

Quick facts

Lead sponsor	HaEmek Medical Center, Israel
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	50
Start date	26 June 2018
Primary completion	26 June 2018
Estimated completion	26 June 2018
Sites	1 location across Israel

Drugs / interventions tested

• probiotic - Lactobacillus reuteri
• placebo - with no active ingredient

Conditions studied

• Functional Constipation — all drugs for Functional Constipation →

Sponsor

HaEmek Medical Center, Israel

Who can join

Adults 6 Months to 15, any sex, with Functional Constipation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Functional constipation (FC) is a common condition in childhood, with an estimated prevalence of 0.7% to 29%.The diagnosis and treatment of FC can be difficult tasks, and children are often referred to specialist services causing treatment to become expensive and time-consuming.The standard treatment based on osmotic laxatives (mainly PEG). The recovery rate is 50% to 60% after 1 year of treatment, with 50% of the children having relapse within 5 years. Studies in adults have established the effectiveness of some lactic acid bacteria in the treatment of chronic constipation.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.