Last reviewed · How we verify
NCT03331159
Evaluation of Fusion After ALIF With an Osteoinductive Material or With Homologus Bone
NA trial testing NanoBone in Fusion of Spine, Lumbar Region in 20 participants. Completed in 31 October 2015.
31 October 2013
Quick facts
| Lead sponsor | Johann Wolfgang Goethe University Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 1 July 2012 |
| Primary completion | 31 October 2013 |
| Estimated completion | 31 October 2015 |
Drugs / interventions tested
- NanoBone
- Homologous Bone
Conditions studied
- Fusion of Spine, Lumbar Region — all drugs for Fusion of Spine, Lumbar Region →
Sponsor
Johann Wolfgang Goethe University Hospital
Who can join
18 and older, any sex, with Fusion of Spine, Lumbar Region. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study was to determine whether instrumented anterior lumbar interbody Fusion with a new nanocrystalline hydroxyapatite embedded in a silica gel matrix (NH-SiO2) was associated with superior radiological and clinical outcomes at 12 months follow-up compared with instrumented ALIF with homologous bone
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Precision medicine strategies for spinal degenerative diseases: Injectable biomaterials with in situ repair and regeneration.
Zhao X, Ma H, Han H, Zhang L, et al · · 2022 · cited 22× · PMID 35799898 · DOI 10.1016/j.mtbio.2022.100336
Verify or expand the search:
- PubMed search for NCT03331159
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of NanoBone
Trials testing the same drug.
- NCT04615260 — Rate of Bony Fusion Using NanoBone® Synthetic Bone Graft Versus Local Autologous Bone Graft. · NA · active not recruiting
Other recruiting trials for Fusion of Spine, Lumbar Region
Currently open trials in the same condition.
- NCT06528288 — Effects of Erector Spinae Plane Block on Postoperative Pain Following Lumbar Fusion Surgery · NA · recruiting
- NCT03770338 — Preoperative Teriparatide Use on Insertional Torque of Pedicle Screws for Lumbar Fusion Surgery · NA · recruiting
Other Johann Wolfgang Goethe University Hospital trials
Trials by the same sponsor.
- NCT05921136 — Recycling Potential in Endoscopy - a Multicentre Prospective Observational Study · unknown
- NCT04739020 — Respiratory Aerosols in Patients With COVID-19 and Healthy Controls · NA · unknown
- NCT04975490 — Characterization and Pathogenesis of ACLF · unknown
- NCT04546867 — Establishing a Sonographic Based Algorithm to Verify Pancreatic Stent Position Placed to Prevent Post-ERCP Pancreatitis · NA · completed
- NCT04476498 — Prospective Comparison of Pull-PEG and Pull-PEG With Gastropexy · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03331159 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Johann Wolfgang Goethe University Hospital
- Last refreshed: 6 November 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03331159.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing