NCT03326739

Ultrasound Guided Versus Landmark Guided Arterial Line Placement by Emergency Medicine Interns

Completed NA Last updated 22 January 2020

What this trial tests

NA trial testing Arterial Line Placement in Vascular Access Complication in 40 participants. Completed in 31 December 2019.

Timeline

1 January 2017

Primary endpoint
31 December 2019

31 December 2019

Quick facts

Lead sponsor	Temple University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	diagnostic
Enrollment	40
Start date	1 January 2017
Primary completion	31 December 2019
Estimated completion	31 December 2019
Sites	1 location across United States

Drugs / interventions tested

• Arterial Line Placement

Conditions studied

• Vascular Access Complication — all drugs for Vascular Access Complication →

Sponsor

Temple University

Who can join

Adults 18 to 99, any sex, with Vascular Access Complication. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Critically ill patients in the emergency department commonly require arterial line placement for continuous direct blood pressure monitoring, frequent arterial blood gas sampling, and frequent blood sampling. Trans-radial catheterization has been shown to reduce access site complications and increase patient comfort compared to trans-femoral access. Radial artery access on the first attempt is optimal; attempts at reentry delay care and increase the risk of vascular spasm, hematoma, infection, neurovascular injury, and pain. The traditional pulse palpation method of radial artery cannulation can be challenging, especially in patients with weak pulses (i.e. morbidly obese or hypotensive individuals).

A review of literature suggests that ultrasound guided trans-radial catheterization compared to standard pulse palpation reduces access time and increases rate of first-entry success when performed by physicians trained in ultrasound. Thus, complications ascribed to reentry are prevented and timely care is provided.

To the investigator's knowledge, only one other prospective study has been conducted to assess the utility of ultrasound guided radial artery cannulation in the emergency department. Due to the paucity of literature to support the use of ultrasound guided trans-radial catheterization in critically ill patients, the study will aim to provide further data on the topic. Both techniques are considered standard of care.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

1. Ultrasound Guidance Versus Landmark-Guided Palpation for Radial Arterial Line Placement by Novice Emergency Medicine Interns: A Randomized Controlled Trial.
   Gibbons RC, Zanaboni A, Saravitz SM, Costantino TG. · · 2020 · cited 12× · PMID 32917440 · DOI 10.1016/j.jemermed.2020.07.029
2. Ultrasound guidance for arterial (other than femoral) catheterisation in adults.
   Flumignan RL, Trevisani VF, Lopes RD, Baptista-Silva JC, et al · · 2021 · cited 11× · PMID 34637140 · DOI 10.1002/14651858.cd013585.pub2
3. Lung Ultrasound versus Chest X-ray for the Diagnosis of COVID-19 Pneumonia
   · 2023