NCT03324165: RCTAppAlg

Comparing Proposed Algorithm and Current Practice in the Evaluation of Suspected Appendicitis

Status unknown NA Last updated 6 September 2018

What this trial tests

NA trial testing Proposed Algorithm in Acute Appendicitis in 160 participants. Status unknown.

Timeline

1 October 2016

Primary endpoint
30 September 2018

30 September 2018

Quick facts

Lead sponsor	Singapore General Hospital
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	health services research
Enrollment	160
Start date	1 October 2016
Primary completion	30 September 2018
Estimated completion	30 September 2018
Sites	2 locations across Singapore

Drugs / interventions tested

• Proposed Algorithm

Conditions studied

• Acute Appendicitis — all drugs for Acute Appendicitis →

Sponsor

Singapore General Hospital

Who can join

Adults 21 to 80, any sex, with Acute Appendicitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Acute appendicitis is one of the most common causes of acute abdominal pain requiring surgical intervention. In the current era, with diagnostic imaging technique like Computed Tomography (CT), negative appendectomy rates have been greatly reduced. However, the radiation risk with CT poses as a concern. Rules for clinical decision guiding CT utilization is thus essential to minimize unnecessary CT scans, which not only poses a radiation risk but also contributes to increased healthcare costs.

Through the development of an algorithm based on Alvarado Score for the management of acute appendicitis, investigators hope to reduce CT utilization with an acceptable negative appendectomy rate, and hence reducing unnecessary radiation and the healthcare costs involved.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Randomized control trial comparing an Alvarado Score-based management algorithm and current best practice in the evaluation of suspected appendicitis.
   Tan WJ, Acharyya S, Chew MH, Foo FJ, et al · · 2020 · cited 6× · PMID 32357897 · DOI 10.1186/s13017-020-00309-0