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NCT03324074

Assessment of Pyloric Sphincter Physiology

Completed Last updated 2 July 2019
What this trial tests

trial in Physiology of Pyloric Sphincter in 20 participants. Completed in 30 April 2019.

Timeline
31 December 2018
Primary endpoint
30 January 2019
30 April 2019

Quick facts

Lead sponsorAsian Institute of Gastroenterology, India
StatusCompleted
Study typeOBSERVATIONAL
Enrollment20
Start date31 December 2018
Primary completion30 January 2019
Estimated completion30 April 2019
Sites1 location across India

Conditions studied

Sponsor

Asian Institute of Gastroenterology, India

Who can join

Adults 18 to 60, any sex, with Physiology of Pyloric Sphincter. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Pylorus is a tubular structure which contains circular muscle, forming pyloric sphincter which separates stomach and duodenum. The motor activity of the pyloric sphincter is less investigated. Antroduodenal manometry is an invasive and time consuming technique also limited by inability to measure compliance of the sphincter. Recently, a new technique functional lumen imaging probe (FLIP) which is based on principle of impedance planimetry (IP). The endoluminal FLIP (EndoFLIP) EF -100 system uses a multi-detector IP system to produce a 3-dimensional outline of a sphincter. EndoFLIP can measure tissue distensibility and geometric changes through volumetric distention with real-time images. The esophagogastric junction (EGJ) has been well studied using EndoFLIP, studies for assessment of pyloric function are lacking.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Trials by the same sponsor.

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