NCT03322423 is a NA clinical trial of Multifocal Contact Lens 1 in Visual Performance, sponsored by Johnson & Johnson Vision Care, Inc..

Who is sponsoring NCT03322423?

NCT03322423 is sponsored by Johnson & Johnson Vision Care, Inc..

What drugs are being tested in NCT03322423?

Interventions in NCT03322423: Multifocal Contact Lens 1, Multifocal Contact Lens 2, Spherical Contact Lens 2.

What condition does NCT03322423 study?

NCT03322423 studies Visual Performance.

Is NCT03322423 still recruiting?

NCT03322423 is currently completed. Last updated 8 January 2019.

Are results published for NCT03322423?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2019-01-08 · How we verify

NCT03322423

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of Two Marketed Multifocal Contact Lenses

Completed NA Results posted Last updated 8 January 2019

What this trial tests

NA trial testing Multifocal Contact Lens 1 in Visual Performance in 78 participants. Completed in 4 November 2017.

Timeline

11 September 2017

Primary endpoint
4 November 2017

4 November 2017

Quick facts

Lead sponsor	Johnson & Johnson Vision Care, Inc.
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	treatment
Enrollment	78
Start date	11 September 2017
Primary completion	4 November 2017
Estimated completion	4 November 2017
Sites	5 locations across United States

Drugs / interventions tested

Multifocal Contact Lens 1
Multifocal Contact Lens 2
Spherical Contact Lens 2

Conditions studied

Visual Performance — all drugs for Visual Performance →

Sponsor

Johnson & Johnson Vision Care, Inc. — full company profile →

Who can join

Adults 40 to 70, any sex, with Visual Performance. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Distance Binocular Visual Acuity Primary · 1-Week Follow-up

Distance visual acuity was assessed for each subject in both eyes under a high luminance high contrast condition using ETDRS (Early Treatment Diabetic Retinopathy Study) charts.

Group	Value	95% CI
Delefilcon A	-0.056	± 0.0842
Nesofilcon A	-0.075	± 0.0759

Near Binocular Visual Acuity Primary · 1-Week Follow-up

Near visual acuity was assessed for each subject in both eyes under a high luminance high contrast condition using reduced Guillon-Poling Charts.

Group	Value	95% CI
Delefilcon A	0.143	± 0.1084
Nesofilcon A	0.143	± 0.1117

Overall Quality of Vision Secondary · 1-Week Follow-up

Overall quality of vision was assessed using the Contact Lens User Experience™ (CLUE) questionnaire. CLUE is a validated patient-reported outcomes (PRO) questionnaire to assess patient experience attributes of soft contact lenses (comfort, vision, handling, and packaging) in a contact-lens wearing population in the US, ages 18-65. Derived CLUE scores using Item Response Theory (IRT) follow a normal distribution with a population average score of 60 (SD 20), where higher scores indicate a more favorable/positive response with a range of 0-120.

Group	Value	95% CI
Delefilcon A	47.4	± 17.81
Nesofilcon A	49.3	± 19.43

Sponsor's own description

This is a single-masked, randomized, cross-over, dispensing, 6- visit pilot study. The purpose of this clinical study is to evaluate the performance of two marketed multifocal lenses.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Multifocal Contact Lens 1

Trials testing the same drug.

NCT03705130 — Evaluation of Visual Performance With Contact Lenses · completed

Other Johnson & Johnson Vision Care, Inc. trials

Trials by the same sponsor.

NCT07443215 — Evaluation of Effect of Scatter on Visual Performance · NA · recruiting
NCT07174596 — Evaluation of Approved Contact Lenses · NA · completed
NCT07076160 — Pilot Dispensing Study of Two Marketed Daily Disposable Multifocal Contact Lenses · NA · completed
NCT06967129 — Evaluation of Daily Disposable Toric Soft Lenses Manufactured With an Alternative Hydration Process · NA · completed
NCT06864858 — Clinical Evaluation of Two Cosmetic Contact Lenses · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03322423 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Johnson & Johnson Vision Care, Inc.
Last refreshed: 8 January 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03322423.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing