Who is sponsoring NCT03321357?

NCT03321357 is sponsored by Bergman Clinics.

What drugs are being tested in NCT03321357?

Interventions in NCT03321357: five-repetition sit-to-stand test.

What condition does NCT03321357 study?

NCT03321357 studies Degenerative Disc Disease, Spondylolisthesis, Spondylosis, Herniated Nucleus Pulposus, Spinal Stenosis Lumbar, Spinal Diseases, Spinal Instability.

Is NCT03321357 still recruiting?

NCT03321357 is currently completed. Last updated 13 July 2018.

Last reviewed 2018-07-13 · How we verify

NCT03321357: 5RSTS-2

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Retest-reliability and At-home-assessment Feasibility of the 5R-STS

Completed Last updated 13 July 2018

What this trial tests

trial testing five-repetition sit-to-stand test in Degenerative Disc Disease in 100 participants. Completed in 21 June 2018.

Timeline

8 December 2017

Primary endpoint
1 June 2018

21 June 2018

Quick facts

Lead sponsor	Bergman Clinics
Status	Completed
Study type	OBSERVATIONAL
Enrollment	100
Start date	8 December 2017
Primary completion	1 June 2018
Estimated completion	21 June 2018
Sites	1 location across Netherlands

Drugs / interventions tested

five-repetition sit-to-stand test

Conditions studied

Degenerative Disc Disease — all drugs for Degenerative Disc Disease →
Spondylolisthesis — all drugs for Spondylolisthesis →
Spondylosis — all drugs for Spondylosis →
Herniated Nucleus Pulposus — all drugs for Herniated Nucleus Pulposus →

Sponsor

Bergman Clinics

Who can join

Eligibility, any sex, with Degenerative Disc Disease or Spondylolisthesis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The five-repetition sit-to-stand test has been validated and is used primarily in pulmonary medicine and cardiology, and has recently been shown to be a useful tool for the objective assessment of functional impairment in patients with degenerative diseases of the lumbar spine. The goal of this study is to assess the possibility of supervised and unsupervised at-home-assessment. Validation of at-home-assessment would allow the 5R-STS to be easily used as a follow-up tool in clinical trials, for example.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

Five-Repetition Sit-to-Stand Test Performance in Healthy Individuals: Reference Values and Predictors From 2 Prospective Cohorts.
Klukowska AM, Staartjes VE, Vandertop WP, Schröder ML. · · 2021 · cited 26× · PMID 35000330 · DOI 10.14245/ns.2142750.375
Can objective functional impairment in lumbar degenerative disease be reliably assessed at home using the five-repetition sit-to-stand test? A prospective study.
Staartjes VE, Beusekamp F, Schröder ML. · · 2019 · cited 19× · PMID 30680635 · DOI 10.1007/s00586-019-05897-3
Association of maximum back and leg pain severity with objective functional impairment as assessed by five-repetition sit-to-stand testing: analysis of two prospective studies.
Staartjes VE, Klukowska AM, Schröder ML. · · 2020 · cited 5× · PMID 31451936 · DOI 10.1007/s10143-019-01168-3
Predictors of five-repetition sit-to-stand test performance in patients with lumbar degenerative disease.
Klukowska AM, Staartjes VE, Vandertop WP, Schröder ML. · · 2023 · cited 2× · PMID 36477416 · DOI 10.1007/s00701-022-05441-1
Predictors of five-repetition sit-to-stand test performance in patients with lumbar degenerative disease
Klukowska AM, Staartjes VE, Vandertop WP, Schröder ML. · · 2022 · DOI 10.21203/rs.3.rs-1659218/v1

Verify or expand the search:

Other recruiting trials for Degenerative Disc Disease

Currently open trials in the same condition.

NCT07254806 — A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to · Phase 3 · recruiting
NCT04679844 — Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mixed With Au · NA · recruiting
NCT06704919 — Conduit Cages and Fibergraft BG Putty · recruiting
NCT06053242 — Safety, Tolerability, and Effectiveness of Intramuscular Injection of CELZ-201-DDT for the Treatment of Chronic Lower Ba · Phase 1, PHASE2 · recruiting
NCT03810573 — Evaluation of NB1 Bone Graft Following Lumbar Interbody Arthrodesis · NA · recruiting

Other Bergman Clinics trials

Trials by the same sponsor.

NCT05161130 — Predicting Outcomes After Lumbar Fusion for Degenerative Disease · completed
NCT04660656 — Predictive Value of the Five-repetition Sit-to-stand Test After Lumbar Spine surgerySTS-3 Study. · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03321357 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Bergman Clinics
Last refreshed: 13 July 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03321357.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing