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NCT03321292
L-arginine in Treatment of Intrauterine Growth Restriction
NA trial testing L-arginine 1000 mg and Acetylesalicylic acid75mg in Intrauterine Growth Restriction Asymmetrical in 260 participants. Status unknown.
1 December 2018
Quick facts
| Lead sponsor | Ain Shams University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 260 |
| Start date | 15 October 2017 |
| Primary completion | 1 December 2018 |
| Estimated completion | 30 December 2018 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- L-arginine 1000 mg and Acetylesalicylic acid75mg — full drug profile →
- acetylsalicylic acid 75 mg — full drug profile →
Conditions studied
- Intrauterine Growth Restriction Asymmetrical — all drugs for Intrauterine Growth Restriction Asymmetrical →
Sponsor
Ain Shams University
Who can join
Adults 20 to 40, female only, with Intrauterine Growth Restriction Asymmetrical. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Intrauterine growth restriction is an important problem in neonatal care. Intrauterine growth restriction (IUGR) is defined as a fetal weight below the 10th percentile for gestational age. One of the main causes of IUGR is placental insufficiency. Nitric oxide(NO) increases placental blood flow. So,it might be useful to improve IUGR pregnancy outcome .
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Interventions affecting the nitric oxide pathway versus placebo or no therapy for fetal growth restriction in pregnancy.
Pels A, Ganzevoort W, Kenny LC, Baker PN, et al · · 2023 · cited 12× · PMID 37428872 · DOI 10.1002/14651858.cd014498
Verify or expand the search:
- PubMed search for NCT03321292
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03321292 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
- Last refreshed: 14 August 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03321292.
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