Who is sponsoring NCT03319563?

NCT03319563 is sponsored by Mansoura University.

What drugs are being tested in NCT03319563?

Interventions in NCT03319563: Local anesthetic-epinephrine, Saline.

What condition does NCT03319563 study?

NCT03319563 studies Posterior Spine Surgery.

Is NCT03319563 still recruiting?

NCT03319563 is currently completed. Last updated 26 October 2020.

Last reviewed 2020-10-26 · How we verify

NCT03319563

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Kyphoscoliosis Surgery: Blood Conservation and Analgesia

Completed NA Last updated 26 October 2020

What this trial tests

NA trial testing Local anesthetic-epinephrine in Posterior Spine Surgery in 52 participants. Completed in 10 October 2017.

Timeline

11 April 2017

Primary endpoint
10 October 2017

10 October 2017

Quick facts

Lead sponsor	Mansoura University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	supportive care
Enrollment	52
Start date	11 April 2017
Primary completion	10 October 2017
Estimated completion	10 October 2017
Sites	1 location across Egypt

Drugs / interventions tested

Local anesthetic-epinephrine — full drug profile →
Saline

Conditions studied

Posterior Spine Surgery — all drugs for Posterior Spine Surgery →

Sponsor

Mansoura University

Who can join

Adults 8 to 18, any sex, with Posterior Spine Surgery. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Since the first spinal fusion by Hibbs 1911, yet anesthesia for correction of scoliosis is challenging due to frequently associated co-morbidities, the extensive nature of surgery and liability for many complications. Among the major concerns for anesthesiologists are the pain and bleeding. Scoliosis correction accounts for massive blood loss that may exceed more than half of blood volume. There are many strategies for blood conservation; however sometimes some of them may not be suitable. For analgesia, the most frequently loco regional analgesic techniques in spine surgery are intrathecal, epidural or local infiltration techniques. infiltration data reviled inconclusive and heterogeneous results. Our purpose is to optimize blood conservation and analgesia through anatomically based modification of the infiltration technique.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

High-volume, Multilevel Local Anesthetics-Epinephrine Infiltration in Kyphoscoliosis Surgery: Blood Conservation.
Mazy A, Elmaadawy AEA, Serry M, Kassem M. · · 2019 · cited 4× · PMID 31602053 · DOI 10.4103/aer.aer_89_19

Verify or expand the search:

Other Mansoura University trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03319563 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Mansoura University
Last refreshed: 26 October 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03319563.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing