Who is sponsoring NCT03312881?

NCT03312881 is sponsored by Institute of Child Health.

What drugs are being tested in NCT03312881?

Interventions in NCT03312881: quantitative sensory testing, neuroimaging, Patient Reported Outcome Measures.

What condition does NCT03312881 study?

NCT03312881 studies Neuropathic Pain, Child, Only.

Is NCT03312881 still recruiting?

NCT03312881 is currently completed. Last updated 2 February 2022.

Last reviewed 2022-02-02 · How we verify

NCT03312881

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Neuropathic Pain in Children: Multimodal Assessment and Diagnosis

Completed Last updated 2 February 2022

What this trial tests

trial testing quantitative sensory testing in Neuropathic Pain in 160 participants. Completed in 31 December 2021.

Timeline

1 September 2017

Primary endpoint
31 July 2021

31 December 2021

Quick facts

Lead sponsor	Institute of Child Health
Status	Completed
Study type	OBSERVATIONAL
Enrollment	160
Start date	1 September 2017
Primary completion	31 July 2021
Estimated completion	31 December 2021
Sites	1 location across United Kingdom

Drugs / interventions tested

quantitative sensory testing
neuroimaging
Patient Reported Outcome Measures

Conditions studied

Neuropathic Pain — all drugs for Neuropathic Pain →
Child, Only — all drugs for Child, Only →

Sponsor

Institute of Child Health

Who can join

Adults 10 to 18, any sex, with Neuropathic Pain or Child, Only. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Some children experience chronic pain that is related to damage or diseases that affect the nerves that send pain signals. This is known as neuropathic pain. This is not well understood and can be difficult to diagnose. It can often produce unusual feelings such as sensitivity of the skin to light touch. Neuropathic pain is often severe and difficult to treat, and can affect quality of life for the child and family. This study aims to better characterise the symptoms and signs, and impact of neuropathic pain in children.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

The feasibility and acceptability of research magnetic resonance imaging in adolescents with moderate-severe neuropathic pain.
Verriotis M, Moayedi M, Sorger C, Peters J, et al · · 2020 · cited 8× · PMID 32072101 · DOI 10.1097/pr9.0000000000000807
Developmental mechanisms of CPSP: Clinical observations and translational laboratory evaluations.
Walker SM. · · 2022 · cited 7× · PMID 35910395 · DOI 10.1080/24740527.2021.1999796
Sensitivity and Specificity of a Neuropathic Screening Tool (Self-Report Leeds Assessment of Neuropathic Symptoms and Signs, S-LANSS) in Adolescents With Moderate-Severe Chronic Pain.
Walker SM, Peters J, Verriotis M, Farag F, et al · · 2024 · cited 4× · PMID 37741521 · DOI 10.1016/j.jpain.2023.09.006
Amygdalar Functional Connectivity Differences Associated With Reduced Pain Intensity in Pediatric Peripheral Neuropathic Pain.
Verriotis M, Sorger C, Peters J, Ayoub LJ, et al · · 2022 · cited 4× · PMID 35692562 · DOI 10.3389/fpain.2022.918766

Verify or expand the search:

Other recruiting trials for Neuropathic Pain

Currently open trials in the same condition.

NCT07493213 — USG-Guided Shoulder Injections in Frozen Shoulder · NA · recruiting
NCT07493226 — Efficacy of Chemically Distinct Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and Pain Phenotypes in Adhesive Capsulitis · NA · recruiting
NCT06398847 — Virtual Reality (VR) Self-Hypnosis Software · NA · recruiting
NCT07487610 — Relationship Between Neuropathic Pain and Geriatric Assessment Parameters in Patients Aged 80 Years and Older · recruiting
NCT07436806 — SPS Block vs. Surgical Intercostal Block for Chronic Pain After Thoracoscopic Surgery · NA · recruiting

Other Institute of Child Health trials

Trials by the same sponsor.

NCT06602570 — The Mosaic Brain: a New Diagnostic Approach in Focal Epilepsies · not yet recruiting
NCT05984758 — Imaging Based Uveitis Screening for Children With Juvenile Idiopathic Arthritis · NA · not yet recruiting
NCT06115317 — Homonymous Hemianopia in Childhood · NA · unknown
NCT04804631 — Tube Feeding in Children Having a Bone Marrow Transplant · completed
NCT03857607 — Natural History Study of ATP1A3-related Disease · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03312881 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Institute of Child Health
Last refreshed: 2 February 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03312881.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing