Who is sponsoring NCT03310606?

NCT03310606 is sponsored by Central Hospital, Nancy, France.

What drugs are being tested in NCT03310606?

Interventions in NCT03310606: Dosage of serum and peritoneal of the B lactam used for antibiotic treatment.

What condition does NCT03310606 study?

NCT03310606 studies Peritonitis, Critical Illness.

Is NCT03310606 still recruiting?

NCT03310606 is currently status unknown. Last updated 18 January 2019.

Last reviewed 2019-01-18 · How we verify

NCT03310606: SPAC

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Serum and Peritoneal Concentration in Antibiotics During the Surgical Management of Peritonitis

Status unknown NA Last updated 18 January 2019

What this trial tests

NA trial testing Dosage of serum and peritoneal of the B lactam used for antibiotic treatment in Peritonitis in 50 participants. Status unknown.

Timeline

24 October 2017

Primary endpoint
1 March 2019

1 May 2019

Quick facts

Lead sponsor	Central Hospital, Nancy, France
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	other
Enrollment	50
Start date	24 October 2017
Primary completion	1 March 2019
Estimated completion	1 May 2019
Sites	1 location across France

Drugs / interventions tested

Dosage of serum and peritoneal of the B lactam used for antibiotic treatment

Conditions studied

Peritonitis — all drugs for Peritonitis →
Critical Illness — all drugs for Critical Illness →

Sponsor

Central Hospital, Nancy, France

Who can join

18 and older, any sex, with Peritonitis or Critical Illness. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

SPAC is a pilote monocentric prospective study about peritonitis and antibiotics pharmacokinetic and pharmacodynamic. The investigators will included 50 patients during 2 years in the University Hospital of Nancy. The aim of this study is to determine if the beta-lactam dosages recommended by the guidelines for management of intra-abdominal infections (published by the Société française d'anesthésie et de réanimation (Sfar) in december 2015) permitted the achievement of adequatly serum and peritoneal concentrations in the medical and surgical management of peritonitis. The investigators will collected 3 pairs of serum and peritoneal fluid samples at 3 different times: peritoneal incision, arrival in ICU and 24 hours after admission in ICU in order to compare the concentrations and the minimal inhibitor concentration of bacteria. The hypothesis is that of a serum and peritoneal antibiotic under dosage.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Serum and peritoneal exudate concentrations after high doses of β-lactams in critically ill patients with severe intra-abdominal infections: an observational prospective study.
Leon L, Guerci P, Pape E, Thilly N, et al · · 2020 · cited 13× · PMID 31599951 · DOI 10.1093/jac/dkz407

Verify or expand the search:

Other recruiting trials for Peritonitis

Currently open trials in the same condition.

NCT04604730 — Role of Protective Stoma After Primary Anastomosis for Generalized Peritonitis Due to Perforated Diverticulitis · NA · recruiting

Other Central Hospital, Nancy, France trials

Trials by the same sponsor.

NCT06452290 — PET Biomarker Study for Antidepressant Response Prediction in Major Depressive Disorder · NA · not yet recruiting
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NCT07414667 — Primary Sjögren's Syndrome: Impact of Quantitative Anti-Ro52 Antibody Analysis on Patient Prognosis and Stratification ( · not yet recruiting
NCT07415759 — Imaging of Electrical Properties by MRI: Investigation of Age-Related Changes · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03310606 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Central Hospital, Nancy, France
Last refreshed: 18 January 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03310606.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing