Last reviewed · How we verify
NCT03309748
Phototherapy Remediation of Black Stain
NA trial testing Dental prophylaxis in Dental Deposits in 31 participants. Completed in 30 April 2016.
30 April 2016
Quick facts
| Lead sponsor | Cardenal Herrera University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 31 |
| Start date | 5 May 2014 |
| Primary completion | 30 April 2016 |
| Estimated completion | 30 April 2016 |
Drugs / interventions tested
- Dental prophylaxis
- Dental prophylaxis + antimicrobial photodynamic therapy
Conditions studied
- Dental Deposits — all drugs for Dental Deposits →
- Tooth Discoloration — all drugs for Tooth Discoloration →
- Dental Prophylaxis — all drugs for Dental Prophylaxis →
Sponsor
Cardenal Herrera University
Who can join
18 and older, any sex, with Dental Deposits or Tooth Discoloration. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study investigates the remediation of black-stained tooth surfaces using antimicrobial photodynamic therapy. In this crossover trial, a cohort of patients received standard dental prophylactic cleaning to remove the black stain. Later, following the washout period, (reappearance of the black stain) received photodynamic therapy in addition to the standard cleaning. Stain-free period in each of the arms was the main outcome variable. Additional microbial plaque testing was also carried out.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Antimicrobial Photodynamic Therapy: Latest Developments with a Focus on Combinatory Strategies.
Youf R, Müller M, Balasini A, Thétiot F, et al · · 2021 · cited 95× · PMID 34959277 · DOI 10.3390/pharmaceutics13121995 -
Remediation of adult black dental stains by phototherapy.
Albelda-Bernardo MA, Jovani-Sancho MDM, Veses V, Sheth CC. · · 2018 · cited 6× · PMID 29977603 · DOI 10.1038/s41405-018-0001-9
Verify or expand the search:
- PubMed search for NCT03309748
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Dental prophylaxis
Trials testing the same drug.
- NCT03544658 — Intervening Factors in Tooth Color Assessment · NA · unknown
- NCT03483376 — aPDT for the Remediation of Dental Black Stain · NA · completed
Other Cardenal Herrera University trials
Trials by the same sponsor.
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- NCT07499856 — Intradialytic Exercise Program Supported by Audiovisual Media Combined With Mindfulness · NA · enrolling by invitation
- NCT07275112 — Cross-cultural an Reliability and Validity Evaluation of TENDINS-A in Spain · completed
- NCT07133581 — Design and Validation of FEXO: A Playful Exercise Program for Institutionalized Frail Older Adults · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03309748 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cardenal Herrera University
- Last refreshed: 17 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03309748.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing