NCT03308851 is a NA clinical trial of Piezocorticision in Piezocorticision, sponsored by Université de Montréal.

Who is sponsoring NCT03308851?

NCT03308851 is sponsored by Université de Montréal.

What drugs are being tested in NCT03308851?

Interventions in NCT03308851: Piezocorticision, Osteoperforation.

What condition does NCT03308851 study?

NCT03308851 studies Piezocorticision, Osteoperforation, Canine Retraction, Orthodontic Treatment.

Is NCT03308851 still recruiting?

NCT03308851 is currently terminated. Last updated 10 June 2021.

Last reviewed 2021-06-10 · How we verify

NCT03308851

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of the Effects of Osteoperforation and Piezocorticision on Canine Retraction

Terminated NA Last updated 10 June 2021

What this trial tests

NA trial testing Piezocorticision in Piezocorticision in 17 participants. Terminated before completion.

Timeline

1 January 2018

Primary endpoint
30 April 2021

30 April 2021

Quick facts

Lead sponsor	Université de Montréal
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	treatment
Enrollment	17
Start date	1 January 2018
Primary completion	30 April 2021
Estimated completion	30 April 2021
Sites	1 location across Canada

Drugs / interventions tested

Piezocorticision
Osteoperforation

Conditions studied

Piezocorticision — all drugs for Piezocorticision →
Osteoperforation — all drugs for Osteoperforation →
Canine Retraction — all drugs for Canine Retraction →
Orthodontic Treatment — all drugs for Orthodontic Treatment →

Sponsor

Université de Montréal — full company profile →

Who can join

16 and older, any sex, with Piezocorticision or Osteoperforation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The primary objective of this research is to compare the rate of canine retraction following the osteoperforation and piezocorticision procedures in cases of first premolar extractions. The secondary objectives are to compare the second order movement of the canine (tipping), the amount of root resorption associated with the procedures, the inflammation process by measuring the inflammatory markers in the gingival crevicular fluid, the loss of posterior anchorage by measures on the cone beam computed tomography (CBCT) 3-dimensional radiograph and on the casts and to evaluate the pain level and the impact on quality of life following each procedure using the questionnaire of the visual analogue scale (VAS) of pain.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The Effectiveness of Repetition or Multiplicity of Different Surgical and Non-Surgical Procedures Compared to a Single Procedure Application in Accelerating Orthodontic Tooth Movement: A Systematic Review and Meta-Analysis.
Alfailany DT, Hajeer MY, Aljabban O, Mahaini L. · · 2022 · cited 13× · PMID 35296053 · DOI 10.7759/cureus.23105

Verify or expand the search:

Other Université de Montréal trials

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03308851 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Université de Montréal
Last refreshed: 10 June 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03308851.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing