NCT03306186 (INTELLIGENCE-1) is a NA clinical trial of HemoSpec in Sepsis, sponsored by University of Athens.

Who is sponsoring NCT03306186?

NCT03306186 is sponsored by University of Athens.

What drugs are being tested in NCT03306186?

Interventions in NCT03306186: HemoSpec.

Is NCT03306186 still recruiting?

NCT03306186 is currently completed. Last updated 15 May 2018.

Last reviewed 2018-05-15 · How we verify

NCT03306186: INTELLIGENCE-1

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Hemospec Device for the Diagnosis of Sepsis

Completed NA Last updated 15 May 2018

What this trial tests

NA trial testing HemoSpec in Sepsis in 183 participants. Completed in 31 March 2018.

Timeline

9 October 2017

Primary endpoint
30 December 2017

31 March 2018

Quick facts

Lead sponsor	University of Athens
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	diagnostic
Enrollment	183
Start date	9 October 2017
Primary completion	30 December 2017
Estimated completion	31 March 2018
Sites	5 locations across Greece

Drugs / interventions tested

HemoSpec

Conditions studied

Sepsis — all drugs for Sepsis →

Sponsor

University of Athens

Who can join

18 and older, any sex, with Sepsis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A diagnostic devise, namely HemoSpec, had been developed that integrates clinical information, along with information on circulating protein biomarkers and the morphology of white blood cells to achieve early diagnosis of sepsis. The current study is aiming to validate and improve performance of HemoSpec for the rapid assessment of the critically ill patient.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

Presepsin as a diagnostic and prognostic biomarker of severe bacterial infections and COVID-19.
Kyriazopoulou E, Leventogiannis K, Tavoulareas G, Mainas E, et al · · 2023 · cited 16× · PMID 36882572 · DOI 10.1038/s41598-023-30807-5
38th International Symposium on Intensive Care and Emergency Medicine : Brussels, Belgium. 20-23 March 2018.
· 2018 · cited 8× · PMID 32831123 · DOI 10.1186/s13054-018-1973-5
39th International Symposium on Intensive Care and Emergency Medicine : Brussels, Belgium, 19-22 March 2019.
· 2019 · cited 3× · PMID 30890150 · DOI 10.1186/s13054-019-2358-0
Blood Biomarker and Raman Analysis of Leukocytes in the Multicenter Intelligence Trials: At the Intensive Care Unit (Intelligence-1) and the Emergency Department (Intelligence-2).
Giamarellos-Bourboulis EJ, Thomas-Rüddel D, Pistiki A, Ramoji A, et al · · 2026 · PMID 40997262 · DOI 10.1097/shk.0000000000002699
Editorial Introduction to the Supplement "Diagnosis of Infectious Diseases by Detection of Microbial Pathogens: A Joint Session Between HemoSpec FrameWork 7 Consortium with COST Action BM1401 Raman4Clinics Working Group 2".
Giamarellos-Bourboulis EJ. · · 2018 · PMID 29549656 · DOI 10.1007/s40121-018-0190-5

Verify or expand the search:

Other recruiting trials for Sepsis

Currently open trials in the same condition.

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NCT07448805 — Accuracy and Safety of the Syai Tag System for Continuous Glucose Monitoring in Intensive Internal Care Unit · NA · recruiting

Other University of Athens trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03306186 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Athens
Last refreshed: 15 May 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03306186.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing