Who is sponsoring NCT03298269?

NCT03298269 is sponsored by University of Utah.

What drugs are being tested in NCT03298269?

Interventions in NCT03298269: Mindfulness-Oriented Recovery Enhancement, Supportive Counseling.

What condition does NCT03298269 study?

NCT03298269 studies Chronic Pain.

Is NCT03298269 still recruiting?

NCT03298269 is currently completed. Last updated 10 December 2021.

Last reviewed 2021-12-10 · How we verify

NCT03298269

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Behavioral Interventions for Chronic Pain and Opioid-Related Problems

Completed NA Last updated 10 December 2021

What this trial tests

NA trial testing Mindfulness-Oriented Recovery Enhancement in Chronic Pain in 95 participants. Completed in 1 October 2020.

Timeline

26 September 2017

Primary endpoint
1 October 2020

1 October 2020

Quick facts

Lead sponsor	University of Utah
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	95
Start date	26 September 2017
Primary completion	1 October 2020
Estimated completion	1 October 2020
Sites	1 location across United States

Drugs / interventions tested

Mindfulness-Oriented Recovery Enhancement
Supportive Counseling

Conditions studied

Chronic Pain — all drugs for Chronic Pain →

Sponsor

University of Utah

Who can join

Adults 18 to 100, any sex, with Chronic Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to examine the effects of Mindfulness-Oriented Recovery Enhancement versus a social support group (supportive counseling) intervention for chronic pain patients receiving long-term opioid pharmacotherapy for pain.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Mindfulness-oriented recovery enhancement reduces opioid misuse risk via analgesic and positive psychological mechanisms: A randomized controlled trial.
Garland EL, Hanley AW, Riquino MR, Reese SE, et al · · 2019 · cited 110× · PMID 31556669 · DOI 10.1037/ccp0000390
Mindfulness-Oriented Recovery Enhancement remediates hedonic dysregulation in opioid users: Neural and affective evidence of target engagement.
Garland EL, Atchley RM, Hanley AW, Zubieta JK, et al · · 2019 · cited 73× · PMID 31663023 · DOI 10.1126/sciadv.aax1569
Mindfulness-oriented recovery enhancement reduces opioid dose in primary care by strengthening autonomic regulation during meditation.
Garland EL, Hudak J, Hanley AW, Nakamura Y. · · 2020 · cited 35× · PMID 32915027 · DOI 10.1037/amp0000638
Mindfulness-induced endogenous theta stimulation occasions self-transcendence and inhibits addictive behavior.
Garland EL, Hanley AW, Hudak J, Nakamura Y, et al · · 2022 · cited 23× · PMID 36223472 · DOI 10.1126/sciadv.abo4455

Verify or expand the search:

Other trials of Mindfulness-Oriented Recovery Enhancement

Trials testing the same drug.

NCT05537961 — Impact of Mindfulness Training on Adolescent Well-Being and Behavior · NA · completed
NCT04824521 — A Pilot Feasibility Study of Mindfulness-Oriented Recovery Enhancement With Pregnant Women With Opioid Use Disorder · NA · terminated
NCT04902339 — Near-infrared Spectroscopy-based Neurofeedback as Adjunct to Mindfulness-Oriented Recovery Enhancement in Persons With C · NA · completed

Other recruiting trials for Chronic Pain

Currently open trials in the same condition.

NCT07491549 — The Effect of Pain Education Group Therapy and Its Impact on Chronic Pain, Kinesiophobia, and Physical Activity · NA · recruiting
NCT07425691 — SPACE for Youth With Chronic Pain · recruiting
NCT07103135 — Optimizing Accelerated TMS for Chronic Pain With Thompson Sampling · Phase 1 · recruiting
NCT06219408 — CIH Stepped Care for Co-occurring Chronic Pain and PTSD · NA · recruiting
NCT07270406 — Healthy Behaviors for Insomnia Prevention in People With HIV and Ongoing Pain · NA · recruiting

Other University of Utah trials

Trials by the same sponsor.

NCT07515755 — Supplemental Oxygen and Oxygen Desaturations in Colonoscopies · NA · not yet recruiting
NCT07225426 — Personalizing Financial Incentives · NA · recruiting
NCT06716411 — Confirming the Effects of Acupuncture Treatments to Relieve Symptoms of Gulf War Illness · NA · recruiting
NCT07246538 — Positive Airway Pressure (PAP) System Evaluation in Volunteers · NA · not yet recruiting
NCT04208984 — Diversion Device With Breath Control · withdrawn

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03298269 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Utah
Last refreshed: 10 December 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03298269.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing