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NCT03297918
Impact of a Structural Phonation Training on Respiratory Muscle Function in Patients With Structural Heart Disease
NA trial testing Respiratory muscle training in Heart Failure in 24 participants. Completed in 10 October 2018.
18 August 2018
Quick facts
| Lead sponsor | University Hospital, Basel, Switzerland |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 24 |
| Start date | 15 February 2018 |
| Primary completion | 18 August 2018 |
| Estimated completion | 10 October 2018 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- Respiratory muscle training
Conditions studied
- Heart Failure — all drugs for Heart Failure →
- Congenital Heart Disease — all drugs for Congenital Heart Disease →
Sponsor
University Hospital, Basel, Switzerland
Who can join
18 and older, any sex, with Heart Failure or Congenital Heart Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Most patients with complex congenital heart disease and cardiomyopathy from acquired heart disease have reduced exercise capacity. Exercise capacity is associated with respiratory muscle strength and function. If structured respiratory muscle training positively influences respiratory muscle function in patients with structural heart disease is not well known. The aim of this study is to investigate whether regular singing lessons and breathing exercises improve respiratory muscle strength in patients with congenital or acquired structural heart disease.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
The molecular mechanisms of cardiac development and related diseases.
Li Y, Du J, Deng S, Liu B, et al · · 2024 · cited 53× · PMID 39715759 · DOI 10.1038/s41392-024-02069-8 -
Physical activity interventions for people with congenital heart disease.
Williams CA, Wadey C, Pieles G, Stuart G, et al · · 2020 · cited 40× · PMID 33112424 · DOI 10.1002/14651858.cd013400.pub2 -
Choir singing improves respiratory muscle strength and quality of life in patients with structural heart disease - HeartChoir: a randomised clinical trial.
Ganzoni C, Arslani K, Pfister O, Freese M, et al · · 2020 · cited 5× · PMID 33038262 · DOI 10.4414/smw.2020.20346
Verify or expand the search:
- PubMed search for NCT03297918
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Respiratory muscle training
Trials testing the same drug.
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- NCT05608941 — High-Intensity Respiratory Muscle Training in Individuals With Parkinson's Disease · NA · completed
- NCT05904600 — Respiratory Muscle Training in Adults With Spinal Cord Injury · NA · unknown
- NCT05533151 — The Influence of Telerehabilitation Focused on Respiratory Muscle Training · NA · unknown
- NCT04929990 — The Effect of Respiratory Muscle Training for Patients With COPD and Mild Cognitive Impairment · NA · completed
Other recruiting trials for Heart Failure
Currently open trials in the same condition.
- NCT06118983 — Improving TRansitions ANd OutcomeS for Heart FailurE Patients in Home Health CaRe (I-TRANSFER-HF) · NA · recruiting
- NCT07496372 — Efficacy and Safety of Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Injection (HiCM-188) in Advanced Heart · Phase 3 · recruiting
- NCT07527156 — Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure · Phase 4 · recruiting
- NCT07263035 — Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure · Phase 4 · recruiting
- NCT07531966 — Vascular Complications After Kidney Transplantation · recruiting
Other University Hospital, Basel, Switzerland trials
Trials by the same sponsor.
- NCT07444788 — Acute Effects of Intravenous 5-MeO-DMT in Healthy Participants · Phase 1 · recruiting
- NCT07494214 — Acute Analgesic Effects of MDMA on Experimentally Induced Acute Pain, Hyperalgesia and Allodynia in Healthy Participants · Phase 1 · recruiting
- NCT07419048 — Artificial Intelligence or Human Hand? Evaluating Inferior Vena Cava Imaging for Hydration Status · recruiting
- NCT06978777 — Effect of Caffeine on Cold-stimulated Brown Adipose Tissue Activity · NA · recruiting
- NCT07273630 — Effect of Protein Supplementation and Fluid Restriction on Plasma Sodium Levels in Patients Undergoing Pituitary Surgery · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03297918 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Basel, Switzerland
- Last refreshed: 11 October 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03297918.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing