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NCT03293446: AC/DC
AC/DC Study: Acidification Test in Patients With Chronic Kidney Disease and Healthy Controls
NA trial testing Urinary acidification test in Chronic Kidney Disease stage4 in 29 participants. Completed in 11 November 2018.
11 November 2018
Quick facts
| Lead sponsor | Erasmus Medical Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 29 |
| Start date | 7 October 2016 |
| Primary completion | 11 November 2018 |
| Estimated completion | 11 November 2018 |
| Sites | 1 location across Netherlands |
Drugs / interventions tested
- Urinary acidification test
Conditions studied
- Chronic Kidney Disease stage4 — all drugs for Chronic Kidney Disease stage4 →
Sponsor
Erasmus Medical Center
Who can join
Adults 18 to 99, male only, with Chronic Kidney Disease stage4. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In this study the effect of an acute acid load on the intrarenal renin angiotensin-system is evaluated in patients with chronic kidney disease and healthy controls
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Acute acid load in chronic kidney disease increases plasma potassium, plasma aldosterone and urinary renin.
Bovée DM, Janssen JW, Zietse R, J Danser AH, et al · · 2020 · cited 2× · PMID 32710099 · DOI 10.1093/ndt/gfaa136
Verify or expand the search:
- PubMed search for NCT03293446
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Chronic Kidney Disease stage4
Currently open trials in the same condition.
- NCT07309094 — Clinical, Morphometric and Biochemical Effects on Adiposopathy Associated With the Use of GLP-1RA in CKD · recruiting
Other Erasmus Medical Center trials
Trials by the same sponsor.
- NCT07406269 — Clinical Evaluation of AI Decision Support for Early Rehabilitation After Surgery · NA · not yet recruiting
- NCT07402109 — CBCT Guided Markerless SBRT for Renal Cell Cancer · NA · recruiting
- NCT07383194 — Prediction Models for LDLT Outcomes · not yet recruiting
- NCT07426575 — Evaluating the Usability of New Dialysis Bags · not yet recruiting
- NCT07329296 — The Regenerative Capacity of the Donor Liver After Living Donor Liver Transplantation: an Ambidirectional Cohort Study · enrolling by invitation
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03293446 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Erasmus Medical Center
- Last refreshed: 20 June 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03293446.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing