NCT03293264

Exercise Training on Metabolic Syndrome Severity in Employees

Completed NA Last updated 29 June 2025

What this trial tests

NA trial testing Exercise training group in Metabolic Syndrome in 314 participants. Completed in 8 July 2023.

Timeline

17 October 2017

Primary endpoint
17 December 2022

8 July 2023

Quick facts

Lead sponsor	Hannover Medical School
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	health services research
Enrollment	314
Start date	17 October 2017
Primary completion	17 December 2022
Estimated completion	8 July 2023
Sites	1 location across Germany

Drugs / interventions tested

• Exercise training group

Conditions studied

• Metabolic Syndrome — all drugs for Metabolic Syndrome →

Sponsor

Hannover Medical School

Who can join

18 and older, any sex, with Metabolic Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Hypothesis: An occupational 6 months physical exercise training will lead to better health behaviour and improve the severity of the metabolic syndrome.

312 subjects will be assigned to either an intervention or a waiting-control-group. The intervention group will receive instructions with the aim to perform 150 min exercise training per week. Exercise consists of endurance, strength and coordination training. A feedback system guided by sports scientists will be installed for all subjects in the intervention group using activity monitoring (wearable). After 6 months training subjects from the intervention group will be assigned to one of the following groups for follow-up observation from month 6 to months 12:

* training with personal/individual feedback from sport scientist
* training with automated feedback using activity monitoring Tools (wearable)
* training without further feedback Subjects assigned to the control group will be provided with information on low intensity motion exercises. After 6 months in the control group subjects will be provided with the same exercise intervention as the intervention for a duration of 6 months.

Study visits will be conducted at month 0, month 6, month 12, and a long-term follow-up at month 24..

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

1. Telemonitoring-supported exercise training, metabolic syndrome severity, and work ability in company employees: a randomised controlled trial.
   Haufe S, Kerling A, Protte G, Bayerle P, et al · · 2019 · cited 44× · PMID 31204284 · DOI 10.1016/s2468-2667(19)30075-1
2. Telemonitoring-Supported Exercise Training in Employees With Metabolic Syndrome Improves Liver Inflammation and Fibrosis.
   Haufe S, Hupa-Breier KL, Bayerle P, Boeck HT, et al · · 2021 · cited 10× · PMID 34140456 · DOI 10.14309/ctg.0000000000000371
3. Employers With Metabolic Syndrome and Increased Depression/Anxiety Severity Profit Most From Structured Exercise Intervention for Work Ability and Quality of Life.
   Haufe S, Kahl KG, Kerling A, Protte G, et al · · 2020 · cited 10× · PMID 32625123 · DOI 10.3389/fpsyt.2020.00562
4. The Impact of Body Weight Changes versus Exercise Capacity Changes on Health-Related Factors following a Lifestyle Intervention in Employees with Metabolic Syndrome.
   Bayerle P, Haufe S, Kück M, Protte G, et al · · 2022 · cited 4× · PMID 36364823 · DOI 10.3390/nu14214560