NCT03292978 is a NA clinical trial of probiotics intervention in Healthy, sponsored by Huilian Zhu.

Who is sponsoring NCT03292978?

NCT03292978 is sponsored by Huilian Zhu.

What drugs are being tested in NCT03292978?

Interventions in NCT03292978: probiotics intervention, non-probiotic control.

Is NCT03292978 still recruiting?

NCT03292978 is currently completed. Last updated 13 November 2019.

Last reviewed 2019-11-13 · How we verify

NCT03292978

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

An Intervention on Healthy Adults of Probiotics on Gut Flora Metabolisms of Choline

Completed NA Last updated 13 November 2019

What this trial tests

NA trial testing probiotics intervention in Healthy in 40 participants. Completed in 31 December 2018.

Timeline

1 July 2017

Primary endpoint
31 December 2017

31 December 2018

Quick facts

Lead sponsor	Huilian Zhu
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	basic science
Enrollment	40
Start date	1 July 2017
Primary completion	31 December 2017
Estimated completion	31 December 2018
Sites	1 location across China

Drugs / interventions tested

probiotics intervention
non-probiotic control

Conditions studied

Healthy — all drugs for Healthy →

Sponsor

Huilian Zhu

Who can join

Adults 18 to 30, male only, with Healthy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the study is to examine the effects of probiotics intervention on choline metabolites and intestinal microbiota composition using a randomized double blind clinical trial. Also, we proposed to explore the real-time change of choline metabolites after probiotics intervention through a PC challenge test. Our study will clarify the biochemical pathway involved in metabolic diseases and hope to provide a new targeted-preventive and therapeutic strategy for chronic metabolic diseases.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effects of probiotic supplementation on serum trimethylamine-N-oxide level and gut microbiota composition in young males: a double-blinded randomized controlled trial.
Chen S, Jiang PP, Yu D, Liao GC, et al · · 2021 · cited 30× · PMID 32440731 · DOI 10.1007/s00394-020-02278-1

Verify or expand the search:

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Other Huilian Zhu trials

Trials by the same sponsor.

NCT06972524 — Effects of Milk Probiotics Intervention on Blood Glucose Control Middle-aged and Elderly People With Pre-diabetes · NA · not yet recruiting
NCT06863766 — Effects of Milk Powder Intervention on Blood Glucose Control and Fluctuation in Middle-aged and Elderly People With Pre- · NA · not yet recruiting
NCT05432180 — Human Milk Nutrients and Infants' Health Outcomes in South China · completed
NCT03720249 — Effects of Supplementation of Compound Nutrients on Plasma Homocysteine in Chinese Adults With Hyperhomocysteinemia · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03292978 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Huilian Zhu
Last refreshed: 13 November 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03292978.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing