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NCT03290495
Ketamine Effect on Isoflurane Anesthesia
Phase 4 trial testing ketamine in Post-anesthesia Recovery in 30 participants. Completed in 25 November 2017.
15 November 2017
Quick facts
| Lead sponsor | Minia University |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | basic science |
| Enrollment | 30 |
| Start date | 30 September 2017 |
| Primary completion | 15 November 2017 |
| Estimated completion | 25 November 2017 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- ketamine (ketamine) — full drug profile →
- saline
Conditions studied
- Post-anesthesia Recovery — all drugs for Post-anesthesia Recovery →
Sponsor
Minia University
Who can join
Adults 18 to 70, any sex, with Post-anesthesia Recovery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Ketamine effect on isoflurane anesthesia This study is designed to study the effect of ketamine on isoflurane anesthesia. As both drugs are hypnotic and are used to cause sleep during surgery and other painful procedures, it was long believed that the actions of two drugs add to each other. For example if a man received both drugs, this man will become awake from anesthesia much later than if this man was given either of them alone. However recent studies showed that this is not the case and ketamine can cause fast recovery from hypnotic effects of isoflurane. This was confirmed in animals. The aim of current study is to investigate if this effect applies for humans, using a state of art brain monitoring device in wide use nowadays called BIS or bispectral index. This device can also shed some light on how ketamine can cause, if any, fast recovery from isoflurane anesthesia. Simply, by studying electrical wave coming from brain to head skin.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03290495
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of ketamine
Trials testing the same drug.
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- NCT07022821 — Comparison of Dexmedetomidine + Ketamine for Postoperative Pain in C-Section · Phase 4 · recruiting
Other recruiting trials for Post-anesthesia Recovery
Currently open trials in the same condition.
- NCT06430645 — Effects of Esketamine on Recovery of Consciousness After Propofol Anesthesia · NA · recruiting
Other Minia University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03290495 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Minia University
- Last refreshed: 28 November 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03290495.
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