NCT03289936 (SyncNIV) is a NA clinical trial of NIPPV in Newborn Respiratory Distress, sponsored by University of Turin, Italy.

Who is sponsoring NCT03289936?

NCT03289936 is sponsored by University of Turin, Italy.

What drugs are being tested in NCT03289936?

Interventions in NCT03289936: NIPPV, SNIPPV.

What condition does NCT03289936 study?

NCT03289936 studies Newborn Respiratory Distress, Preterm Infant.

Is NCT03289936 still recruiting?

NCT03289936 is currently status unknown. Last updated 29 November 2023.

Last reviewed 2023-11-29 · How we verify

NCT03289936: SyncNIV

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Short Term Effects of Synchronized vs. Non-synchronized NIPPV in Preterm Infants.

Status unknown NA Last updated 29 November 2023

What this trial tests

NA trial testing NIPPV in Newborn Respiratory Distress in 30 participants. Status unknown.

Timeline

16 November 2020

Primary endpoint
31 December 2024

31 December 2024

Quick facts

Lead sponsor	University of Turin, Italy
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	treatment
Enrollment	30
Start date	16 November 2020
Primary completion	31 December 2024
Estimated completion	31 December 2024
Sites	1 location across Italy

Drugs / interventions tested

NIPPV
SNIPPV

Conditions studied

Newborn Respiratory Distress — all drugs for Newborn Respiratory Distress →
Preterm Infant — all drugs for Preterm Infant →

Sponsor

University of Turin, Italy

Who can join

Under 32 Weeks, any sex, with Newborn Respiratory Distress or Preterm Infant. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Comparing the cardio-respiratory adaptation and differences to non invasive ventilation techniques, nasal intermittent positive pressure ventilation (NIPPV) non synchronized vs synchronized (SNIPPV) in preterm newborns (gestational age at birth \< 32 weeks) at their first approach to non invasive ventilation as first intention (soon after birth) or after extubation.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Short-term effects of synchronized vs. non-synchronized NIPPV in preterm infants: study protocol for an unmasked randomized crossover trial.
Cresi F, Chiale F, Maggiora E, Borgione SM, et al · · 2021 · cited 5× · PMID 34127040 · DOI 10.1186/s13063-021-05351-0
Short term effects of synchronized vs. non-synchronized NIPPV in preterm infants: study protocol for an unmasked randomized crossover trial.
Cresi F, Chiale F, Maggiora E, Borgione SM, et al · · 2021 · DOI 10.21203/rs.3.rs-70166/v1

Verify or expand the search:

Other trials of NIPPV

Trials testing the same drug.

NCT06966752 — Comparison of Continuous Positive Airway Pressure (CPAP) and Non-Invasive Positive Pressure Ventilation (NIPPV) in Prete · NA · recruiting
NCT07000071 — Non-invasive Secondary Respiratory Support in Late Preterm and Term Infants · NA · completed
NCT03842462 — NHFOV vs NIPPV vs nCPAP in Preterm Infants With Respiratory Distress Syndrome · NA · unknown
NCT04698473 — Comparison of Efficacy of Less Invasive Surfactant Treatment Under Nasal CPAP and Nasal IPPV · NA · completed
NCT04282369 — Evaluation Of The Efficacy Of Four Different Non-invasive Ventilation Modes Performed In The Delivery Room · NA · unknown

Other University of Turin, Italy trials

Trials by the same sponsor.

NCT06493188 — Low VS High-fidelity Interprofessional Simulation for ABG Skills Acquisition · NA · not yet recruiting
NCT07418489 — Biotics Intervention Oriented to Rescue From Environmental Pollution Inflammatory Responses · NA · enrolling by invitation
NCT07311291 — The Effect of Different Hemostatic Agents on Hemorrhage Control, Pain and Quality of Life After Endodontic Microsurgery. · NA · completed
NCT06904963 — Efficacy of Oral Hygiene Instructions Carried Out Using an Intra-oral Scanner · NA · completed
NCT07047261 — Efficacy of a Xanthan-based Chlorhexidine Gel in the Treatment of Peri-implant Mucositis · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03289936 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Turin, Italy
Last refreshed: 29 November 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03289936.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing