NCT03284190 (SMASH) is a clinical trial of Surgery in Acute Subdural Hematoma, sponsored by Karolinska University Hospital.

Who is sponsoring NCT03284190?

NCT03284190 is sponsored by Karolinska University Hospital.

What drugs are being tested in NCT03284190?

Interventions in NCT03284190: Surgery.

What condition does NCT03284190 study?

NCT03284190 studies Acute Subdural Hematoma.

Is NCT03284190 still recruiting?

NCT03284190 is currently status unknown. Last updated 6 March 2018.

Last reviewed 2018-03-06 · How we verify

NCT03284190: SMASH

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Scandinavian Multicentre Acute Subdural Hematoma (SMASH) Study

Status unknown Last updated 6 March 2018

What this trial tests

trial testing Surgery in Acute Subdural Hematoma in 1,600 participants. Status unknown.

Timeline

6 March 2018

Primary endpoint
1 October 2018

1 December 2018

Quick facts

Lead sponsor	Karolinska University Hospital
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	1,600
Start date	6 March 2018
Primary completion	1 October 2018
Estimated completion	1 December 2018

Drugs / interventions tested

Surgery

Conditions studied

Acute Subdural Hematoma — all drugs for Acute Subdural Hematoma →

Sponsor

Karolinska University Hospital

Who can join

Eligibility, any sex, with Acute Subdural Hematoma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In a multi-national population-based cohort, the investigators want to compare the clinical course and clinical outcome of elderly patients (≥70 y/o) compared with younger patients (\< 70 y/o) with acute subdural hematoma treated surgically. An improved understanding of the clinical outcome and the prognostic factors of acute subdural hematomas would allow physicians to make better decisions about treatment options in traumatic ASDH in the elderly population.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Scandinavian Multicenter Acute Subdural Hematoma (SMASH) Study: Study Protocol for a Multinational Population-Based Consecutive Cohort.
Bartek J, Laugesen C, Mirza S, Forsse A, et al · · 2019 · cited 4× · PMID 29762769 · DOI 10.1093/neuros/nyy173

Verify or expand the search:

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Other Karolinska University Hospital trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03284190 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Karolinska University Hospital
Last refreshed: 6 March 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03284190.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing