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NCT03277872: NoLint
NoL, HR and MABP Responses to Tracheal Intubation Performed With MAC Blade Versus Glidescope
NA trial testing Laryngoscopy with GlideScope (GVL) Blade in Intubation in 50 participants. Completed in 2 July 2021.
7 November 2017
Quick facts
| Lead sponsor | Ciusss de L'Est de l'Île de Montréal |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | other |
| Enrollment | 50 |
| Start date | 5 September 2017 |
| Primary completion | 7 November 2017 |
| Estimated completion | 2 July 2021 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Laryngoscopy with GlideScope (GVL) Blade
- Laryngoscopy with MacIntosh (MAC) Blade
Conditions studied
- Intubation — all drugs for Intubation →
- Nociceptive Pain — all drugs for Nociceptive Pain →
- Anesthesia — all drugs for Anesthesia →
- Laryngoscopy — all drugs for Laryngoscopy →
Sponsor
Ciusss de L'Est de l'Île de Montréal — full company profile →
Who can join
18 and older, any sex, with Intubation or Nociceptive Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Prospective, randomized and controlled who will be conducted in Maisonneuve-Rosemont hospital and whose objectives are: * To observe if the alterations of the NoL index and the standard monitoring (Mean Arterial Blood Pressure and Heart Rate) (using the variability of NoL index and standard monitoring, peak NoL index and peak standard monitoring values, and number of time passed over their respective threshold for nociceptive response) are more accentuated after laryngoscopy using the classical MAC blade versus single-use disposable blade of the Glidescope. * To observe the nociceptive response (using the variability of NoL index and standard monitoring, peak NoL index and peak standard monitoring values, and number of time passed over their respective threshold for nociceptive response) related to the insertion of endotracheal tube between vocal cords during the intubation. Study plans to enroll 50 adult patients scheduled to undergo either general, gynecological, neurological, orthopedic, plastic or urological surgery under general anesthesia and who necessitate endotracheal intubation.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A randomized controlled trial comparing nociception level (NOL) index, blood pressure, and heart rate responses to direct laryngoscopy versus videolaryngoscopy for intubation: the NOLint project.
Sbeghen V, Verdonck O, McDevitt J, Zaphiratos V, et al · · 2021 · cited 16× · PMID 33709262 · DOI 10.1007/s12630-021-01936-0
Verify or expand the search:
- PubMed search for NCT03277872
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Ciusss de L'Est de l'Île de Montréal trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03277872 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ciusss de L'Est de l'Île de Montréal
- Last refreshed: 4 October 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03277872.
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