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NCT03276325
Epidural Steroids With Intrathecal Nalbuphine for Lower Abdominal Oncologic Surgery
NA trial testing Placebo-nalbuphine in Lower Abdominal Oncologic Surgery in 70 participants. Completed in 7 January 2018.
1 January 2018
Quick facts
| Lead sponsor | Mansoura University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | other |
| Enrollment | 70 |
| Start date | 15 September 2017 |
| Primary completion | 1 January 2018 |
| Estimated completion | 7 January 2018 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Placebo-nalbuphine — full drug profile →
- Dexamethasone-nalbuphine — full drug profile →
Conditions studied
- Lower Abdominal Oncologic Surgery — all drugs for Lower Abdominal Oncologic Surgery →
Sponsor
Mansoura University
Who can join
Adults 18 to 60, any sex, with Lower Abdominal Oncologic Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Intraoperative pain, nausea, vomiting, hypotension, bradycardia are known side effects during lower abdominal surgery under spinal anesthesia, Time to 2 segment regression of sensory block and duration of effective analgesia prolonged with intrathecal (IT) 0.4 mg nalbuphine \& IT 0.8 mg nalbuphine, but the incidence of side-effects was significantly higher with IT 0.8 mg nalbuphine compared with (IT) 0.4 mg nalbuphine.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03276325
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03276325 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mansoura University
- Last refreshed: 9 January 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03276325.
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