NCT03275831 is a NA clinical trial of PluroGel in Venous Ulcer, sponsored by Medline Industries.

Who is sponsoring NCT03275831?

NCT03275831 is sponsored by Medline Industries.

What drugs are being tested in NCT03275831?

Interventions in NCT03275831: PluroGel, Intrasite gel.

What condition does NCT03275831 study?

NCT03275831 studies Venous Ulcer, Arterial Ulcer.

Is NCT03275831 still recruiting?

NCT03275831 is currently terminated. Last updated 20 October 2021.

Last reviewed 2021-10-20 · How we verify

NCT03275831

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

PluroGel on Wounds of Mixed Etiology

Terminated NA Last updated 20 October 2021

What this trial tests

NA trial testing PluroGel in Venous Ulcer in 16 participants. Terminated before completion.

Timeline

8 January 2018

Primary endpoint
5 October 2021

5 October 2021

Quick facts

Lead sponsor	Medline Industries
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	16
Start date	8 January 2018
Primary completion	5 October 2021
Estimated completion	5 October 2021
Sites	2 locations across United Kingdom

Drugs / interventions tested

PluroGel — full drug profile →
Intrasite gel

Conditions studied

Venous Ulcer — all drugs for Venous Ulcer →
Arterial Ulcer — all drugs for Arterial Ulcer →

Sponsor

Medline Industries — full company profile →

Who can join

18 and older, any sex, with Venous Ulcer or Arterial Ulcer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A randomized controlled study (RCT) to investigate the topical effectiveness of PluroGel in healing venous and mixed aetiology leg ulcers. Patients with venous and mixed aetiology leg ulcers will be identified from hospital outpatient clinics. Willing patients meeting the inclusion and exclusion criteria will be consented and assessed in line with standard care. Participants will be randomized at Week 2 to receive either topical PluroGel or Intrasite gel (an alternative topical hydrogel product) if inclusion criteria is met.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Hydrogel dressings for venous leg ulcers.
Ribeiro CT, Dias FA, Fregonezi GA. · · 2022 · cited 13× · PMID 35930364 · DOI 10.1002/14651858.cd010738.pub2
Dressings and topical agents for arterial leg ulcers.
Broderick C, Pagnamenta F, Forster R. · · 2020 · cited 12× · PMID 31978262 · DOI 10.1002/14651858.cd001836.pub4

Verify or expand the search:

Other trials of PluroGel

Trials testing the same drug.

NCT05000983 — A Between Patient Study of Plurogel® Compared to Standard Topical Dressing in Burn Injuries · Phase 1, PHASE2 · recruiting
NCT04893863 — A Study of Plurogel® Compared to Standard Topical Dressing in Burn Injuries · Phase 1, PHASE2 · recruiting

Other recruiting trials for Venous Ulcer

Currently open trials in the same condition.

NCT06031714 — Fetal Cell Receptors Repertoire · NA · recruiting
NCT05805137 — Monitoring of Venous Ulcers Using a Bioimpedance Measurement Based Method and System · NA · recruiting

Other Medline Industries trials

Trials by the same sponsor.

NCT05755282 — Touch and Feel Evaluation of Two Foam Hand Sanitizers · Phase 4 · completed
NCT05740332 — Wet Time for a Foam Hand Sanitizer · Phase 4 · completed
NCT05756348 — Durability of Two Skin Barrier Protectants (SBP) · NA · completed
NCT05742347 — Skin Protectant Textile Efficacy Study for Managing Skin Fold Conditions · NA · terminated
NCT05250102 — Neonatal Pulse Oximetry Sensor Study · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03275831 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Medline Industries
Last refreshed: 20 October 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03275831.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing