Who is sponsoring NCT03274791?

NCT03274791 is sponsored by Ministry of Scientific Research, Tunisia.

What condition does NCT03274791 study?

NCT03274791 studies COPD, Airway Obstruction, Inflammation.

What drugs are being tested in NCT03274791?

Interventions: Analysis of induced sputum, Lung Function test, Enzyme-linked Immunosorbent Assay.

What is the status of NCT03274791?

NCT03274791 is currently COMPLETED.

Last reviewed 2017-09-06 · How we verify

Airway Inflammatory Profile and Clinical Presentation of COPD: A Comparison Between Never Smokers and Smokers

NCT03274791 COMPLETED

The aim of this study was to investigate the airway inflammatory profile and the clinical presentation of chronic obstructive pulmonary disease (COPD) in never smokers compared to smokers with COPD.

Details

Lead sponsor	Ministry of Scientific Research, Tunisia
Status	COMPLETED
Enrolment	68
Start date	2013-09
Completion	2017-01

Conditions

COPD
Airway Obstruction
Inflammation

Interventions

Analysis of induced sputum
Lung Function test
Enzyme-linked Immunosorbent Assay

Primary outcomes

Weight measurement — 6 months
Weight was measured in kilograms for all the participants.
Height measurement — 6 months
Height was measured in meters for all the participants.
Forced vital capacity (FVC) — 6 months
FVC was measured using a portable spirometer (Easy One ndd. Medizintechnik; Zurich, Switzerland) according to the American Thoracic Society criteria.
Forced expiratory volume in one second (FEV1) — 6 months
FEV1 was measured using a portable spirometer (Easy One ndd. Medizintechnik; Zurich, Switzerland) according to the American Thoracic Society criteria.
Sputum induction and collection — 6 months
Sputum induction was conducted by inhalation of nebulised sterile hypertonic saline solution followed by coughing and expectoration of airway secretions. For nebulisation, an ultrasound nebulizer was used for 5-20 min to provide an adequate amount of sample. The subject is asked to cough and expectorate at 5 min intervals.