Last reviewed · How we verify
NCT03269123
A Mechanical Device for Blepharospasm
NA trial testing Pressop 1 in Blepharospasm in 58 participants. Completed in 8 August 2011.
8 August 2011
Quick facts
| Lead sponsor | Oxford University Hospitals NHS Trust |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 58 |
| Start date | 2 March 2010 |
| Primary completion | 8 August 2011 |
| Estimated completion | 8 August 2011 |
Drugs / interventions tested
- Pressop 1
Conditions studied
- Blepharospasm — all drugs for Blepharospasm →
Sponsor
Oxford University Hospitals NHS Trust
Who can join
18 and older, any sex, with Blepharospasm. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Idiopathic blepharospasm (IB) is a rare but well characterised adult onset focal dystonia that may cause severe visual disability. The most effective treatment is with periodic injections of botulinum toxin into the pre-tarsal and / or pre-septal orbicularis oculi muscles bilaterally. However, even with treatment, practical visual function often remains compromised. A subset of IB sufferers find that eye opening improves with focal unilateral digital pressure usually on a specific point on the temple. The Investigators have developed a spectacle mounted spring-loaded prosthesis (the "Pressop" device) to apply continuous individually localised focal pressure on the temple to mimic the effect of finger pressure. The Investigators recommended a trial of this simple safe device in those IB patients who report improvement in eye opening with focal digital temple pressure.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03269123
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Oxford University Hospitals NHS Trust trials
Trials by the same sponsor.
- NCT07303582 — Individualised Cryoneurolysis to Treat Pain in the Context of Spasticity in the Upper and Lower Extremities · Phase 4 · recruiting
- NCT06922695 — Responding to AF: Pill-in-Pocket Anticoagulation Guided by Automated Monitoring and Alerts · NA · recruiting
- NCT06822686 — Autologous Stem Cells in the Management of Fistulating Perianal Crohn's Disease · NA · not yet recruiting
- NCT06397664 — The Impact of Chronic Adolescent Skin Conditions on Sexual Health · completed
- NCT06130397 — AI Assisted Detection of Fractures on X-Rays (FRACT-AI) · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03269123 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Oxford University Hospitals NHS Trust
- Last refreshed: 31 August 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03269123.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing